Comparative evaluation of 4 commercial modified‐live porcine reproductive and respiratory syndrome virus (PRRSV) vaccines against heterologous dual Korean PRRSV‐1 and PRRSV‐2 challenge
Sign Up to like & getrecommendations! Published in 2020 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.282
Abstract: Abstract Background Four commercial porcine reproductive and respiratory syndrome virus (PRRSV) modified‐live vaccines (MLV) was compared to protect growing pigs against dual challenge of PRRSV‐1 and PRRSV‐2. Methods Two of the vaccines were based on… read more here.
Keywords: prrsv vaccines; prrsv mlv; vaccinated groups; mlv vaccinated ... See more keywords
The commercial PRRSV attenuated vaccine can be a potentially effective live trivalent vaccine vector
Sign Up to like & getrecommendations! Published in 2025 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-025-13502-5
Abstract: PRRSV is an immunosuppressive virus that is prone to secondary infection by other viral and microbial pathogens, exacerbating its harm to pigs. The development of multivalent vaccines that can prevent and control multiple pathogens is… read more here.
Keywords: vector; commercial prrsv; prrsv; vaccine ... See more keywords
Griffithsin inhibits porcine reproductive and respiratory syndrome virus infection in vitro
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DOI: 10.1007/s00705-018-4029-x
Abstract: Porcine reproductive and respiratory syndrome virus (PRRSV) is a pathogen that severely disrupts swine production. Despite sustained efforts, the disease is still endemic, with high mortality and morbidity. New antiviral strategies to control PRRSV are needed.… read more here.
Keywords: respiratory syndrome; griffithsin; porcine reproductive; reproductive respiratory ... See more keywords
The glycosyltransferase ST3GAL2 modulates virus proliferation and the inflammation response in porcine reproductive and respiratory syndrome virus infection.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of virology"
DOI: 10.1007/s00705-021-05180-1
Abstract: β-galactoside α-2,3-sialyltransferase 2 (ST3GAL2) is a member of the sialyltransferase family that mediates terminal modification of glycoproteins and glycolipids. ST3GAL2 has been found to play a role in obesity, aging, and malignant diseases. In this… read more here.
Keywords: pst3gal2; proliferation; porcine reproductive; st3gal2 ... See more keywords
Nuclear localization signal in TRIM22 is essential for inhibition of type 2 porcine reproductive and respiratory syndrome virus replication in MARC-145 cells
Sign Up to like & getrecommendations! Published in 2019 at "Virus Genes"
DOI: 10.1007/s11262-019-01691-x
Abstract: Porcine reproductive and respiratory syndrome virus (PRRSV) infection causes one of the most economically important swine diseases worldwide. Tripartite motif-containing 22 (TRIM22), a TRIM family protein, has been identified as a crucial restriction factor that… read more here.
Keywords: porcine reproductive; reproductive respiratory; trim22; replication ... See more keywords
CD163 knockout pigs are fully resistant to highly pathogenic porcine reproductive and respiratory syndrome virus
Sign Up to like & getrecommendations! Published in 2018 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2018.01.004
Abstract: ABSTRACT Porcine reproductive and respiratory syndrome virus (PRRSV) causes severe economic losses to current swine production worldwide. Highly pathogenic PRRSV (HP‐PRRSV), originated from a genotype 2 PRRSV, is more virulent than classical PRRSV and further… read more here.
Keywords: cd163 knockout; highly pathogenic; cd163; virus ... See more keywords
Identification of a linear B-cell epitope on glycoprotein (GP) 2a of porcine reproductive and respiratory syndrome virus (PRRSV).
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.07.171
Abstract: Glycoprotein (GP) 2a was a minor structural protein of porcine reproductive and respiratory syndrome virus (PRRSV) and was one of crucial proteins for PRRSV to bind cell receptor, which indicated that there were neutralizing epitopes… read more here.
Keywords: respiratory syndrome; epitope; porcine reproductive; reproductive respiratory ... See more keywords
Hepatitis B core antigen-based vaccine demonstrates cross-neutralization against heterologous North American Porcine Reproductive and Respiratory Syndrome Virus (PRRSV-2) strains.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of virological methods"
DOI: 10.1016/j.jviromet.2020.113945
Abstract: The U.S. swine industry have been bearing the financial impact of Porcine Reproductive and Respiratory Syndrome (PRRS) for decades. Absent of a safe and efficacious vaccine to combat PRRS virus's genetic heterogeneity, it remains a… read more here.
Keywords: respiratory syndrome; porcine reproductive; reproductive respiratory; hepatitis core ... See more keywords
Alterations in the expression level of visfatin in the lungs of piglets infected with PRRSV and its effect on PRRSV replication.
Sign Up to like & getrecommendations! Published in 2022 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2022.105443
Abstract: Porcine reproductive and respiratory syndrome (PRRS) is a highly contagious disease caused by PRRS virus (PRRSV), characterized by sow reproductive failure and respiratory symptoms in pigs of all ages. PRRSV mainly causes severe lung damage… read more here.
Keywords: visfatin; lung; prrsv; prrsv infection ... See more keywords
The porcine trophoblast cell line PTr2 is susceptible to porcine reproductive and respiratory syndrome virus-2 infection.
Sign Up to like & getrecommendations! Published in 2019 at "Placenta"
DOI: 10.1016/j.placenta.2019.10.004
Abstract: INTRODUCTION Porcine reproductive and respiratory syndrome virus-2 (PRRSV-2) breaches the maternal-fetal interface (MFI) to infect porcine fetuses, yet the exact mechanism(s) of transmission is not understood. The objective of this study was to determine the… read more here.
Keywords: ptr2 cells; microscopy; ptr2; infection ... See more keywords
The impact of porcine reproductive and respiratory syndrome virus (PRRSV) genotypes, established on the basis of ORF-5 nucleotide sequences, on three production parameters in Ontario sow farms.
Sign Up to like & getrecommendations! Published in 2021 at "Preventive veterinary medicine"
DOI: 10.1016/j.prevetmed.2021.105312
Abstract: The porcine reproductive and respiratory syndrome virus (PRRSV) is an enveloped RNA virus, with high mutation rates and genetic variability; which is evident by the large number of discrete strains that co-circulate in swine populations.… read more here.
Keywords: impact; mortality; clinical impact; production parameters ... See more keywords