PRRX1 induced by BMP signaling decreases tumorigenesis by epigenetically regulating glioma-initiating cell properties via DNA methyltransferase 3A.
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DOI: 10.1002/1878-0261.13051
Abstract: Glioma-initiating cells (GICs), a major source of glioblastoma recurrence, are characterized by the expression of neural stem cell markers and the ability to grow by forming non-adherent spheres under serum-free conditions. Bone morphogenetic proteins (BMPs),… read more here.
Keywords: prrx1 induced; cell; glioma initiating; dna methyltransferase ... See more keywords