Heterologous expression of cryptic biosynthetic gene cluster from Streptomyces prunicolor yields novel bicyclic peptide prunipeptin.
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DOI: 10.1016/j.micres.2020.126669
Abstract: Recently, ω-ester-containing peptides (OEPs) were indicated to be a class of ribosomally synthesized and post-translationally modified peptides. Based on genome mining, new biosynthetic gene cluster of OEPs was found in the genome sequence of actinobacterium… read more here.
Keywords: prunipeptin; peptide; biosynthetic gene; gene cluster ... See more keywords