Peroxiredoxin 4 inhibits insulin-induced adipogenesis through regulation of ER stress in 3T3-L1 cells
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-020-03714-w
Abstract: Abstract Obesity was originally considered a disease endemic to developed countries but has since emerged as a global health problem. Obesity is characterized by abnormal or excessive lipid accumulation (World Health Organization, WHO) resulting from… read more here.
Keywords: adipocyte differentiation; adipogenesis; stress; obesity ... See more keywords
Abstract PO-079: Peroxiredoxin 4 contributes to radiation resistance of prostate cancer cells through the activation of the PI3K/AKT signaling pathway
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Cancer Research"
DOI: 10.1158/1557-3265.radsci21-po-079
Abstract: The peroxiredoxin (Prx) family of proteins functions as major cellular antioxidants that mediate oxidative signaling under physiological conditions as well as scavenge extra hydrogen peroxide in the context of oxidative stress. Prx4 is one of… read more here.
Keywords: prx4; prostate cancer; cancer; radiation resistance ... See more keywords
Peroxiredoxin 4 Interacts With Domeless and Participates in Antibacterial Immune Response Through the JAK/STAT Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.907183
Abstract: The JAK/STAT pathway plays an important role in the development and immune responses of animals. In vertebrates, families of cytokines or growth factors act as activators of the JAK/STAT pathway; however, the activators for the… read more here.
Keywords: interacts domeless; peroxiredoxin interacts; stat pathway; jak stat ... See more keywords
Essential Roles of Peroxiredoxin IV in Inflammation and Cancer
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DOI: 10.3390/molecules27196513
Abstract: Peroxiredoxin IV (Prx4) is a 2-Cysteine peroxidase with ubiquitous expression in human tissues. Prx4 scavenges hydrogen peroxide and participates in oxidative protein folding in the endoplasmic reticulum. In addition, Prx4 is secreted outside the cell.… read more here.
Keywords: inflammation; inflammation cancer; roles peroxiredoxin; essential roles ... See more keywords