Maternal separation exacerbates Alzheimer’s disease-like behavioral and pathological changes in adult APPswe/PS1dE9 mice
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DOI: 10.1016/j.bbr.2016.10.030
Abstract: &NA; Alzheimer's disease (AD), the most common neurodegenerative disorder that gradually destroys memory and cognitive abilities in the elderly, makes a huge emotional and economic burden on the patients and their families. The presence of… read more here.
Keywords: ps1de9 mice; appswe ps1de9; maternal separation;
Amelioration of cognitive impairments in APPswe/PS1dE9 mice is associated with metabolites alteration induced by total salvianolic acid
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DOI: 10.1371/journal.pone.0174763
Abstract: Purpose Total salvianolic acid (TSA) is extracted from salvia miltiorrhiza; however, to date, there has been limited characterization of its effects on metabolites in Alzheimer’s disease model-APPswe/PS1dE9 mice. The main objective of this study was… read more here.
Keywords: ps1de9 mice; salvianolic acid; learning memory; mice ... See more keywords