The immunomodulatory protein Dickkopf-1 (DKK1) defines a non-neuroendocrine subtype of metastatic castration-resistant prostate cancer (mCRPC) with low AR and low PSA expression.
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DOI: 10.1200/jco.2017.35.15_suppl.5054
Abstract: 5054Background: Advanced stagemCRPC can manifest AR-signaling independent growth typified by loss of AR and/or PSA expression in the absence of neuroendocrine (NE) features on biopsy. We sought to ... read more here.
Keywords: psa expression; psa; dickkopf dkk1; immunomodulatory protein ... See more keywords