Potential mechanisms for phencyclidine/ketamine-induced brain structural alterations and behavioral consequences.
Sign Up to like & getrecommendations! Published in 2019 at "Neurotoxicology"
DOI: 10.1016/j.neuro.2019.12.005
Abstract: Evidence of structural abnormalities in the nervous system of recreational drug [e.g., phencyclidine (PCP) or ketamine] users and/or preclinical animal research models suggests interference with the activity of multiple neurotransmitters, particularly glutamate neurotransmission. The damage… read more here.
Keywords: pcp ketamine; ketamine induced; psa ncam; ketamine ... See more keywords
Lack of Hypothalamus Polysialylation Inducibility Correlates With Maladaptive Eating Behaviors and Predisposition to Obesity
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2018.00125
Abstract: High variability exists in individual susceptibility to develop overweight in an obesogenic environment and the biological underpinnings of this heterogeneity are poorly understood. In this brief report, we show in mice that the vulnerability to… read more here.
Keywords: psa ncam; lack hypothalamus; hypothalamus polysialylation; inducibility correlates ... See more keywords