Articles with "psca" as a keyword



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Pre-storage cold acclimation maintained quality of cold-stored cucumber through differentially and orderly activating ROS scavengers

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Published in 2017 at "Postharvest Biology and Technology"

DOI: 10.1016/j.postharvbio.2017.03.001

Abstract: Abstract Cucumber fruit are susceptible to chilling injury (CI) during storage and shipping at temperatures below 7–10 °C. Pre-storage cold acclimation (PsCA) is a promising postharvest method for reducing CI and maintaining quality, but the reported… read more here.

Keywords: quality; storage; cucumber; ros scavengers ... See more keywords
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Abstract 1856: Dual-modality immunoPET/fluorescence imaging of prostate cancer utilizing89Zr- or124I-Cy5.5-anti-PSCA cys-minibody

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Published in 2017 at "Cancer Research"

DOI: 10.1158/1538-7445.am2017-1856

Abstract: Prostate cancer patients can benefit from non-invasive and more accurate diagnosis, as well as improved visualization during surgery. ImmunoPET can provide information on location and extent of the disease, while fluorescent image-guided surgery can distinguish… read more here.

Keywords: cancer; tumor; a11 cmb; psca ... See more keywords
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PSCA expression is associated with favorable tumor features and reduced PSA recurrence in operated prostate cancer

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Published in 2018 at "BMC Cancer"

DOI: 10.1186/s12885-018-4547-7

Abstract: BackgroundProstate Stem Cell Antigen (PSCA) is frequently expressed in prostate cancer but its exact function is unclear.MethodsTo clarify contradictory findings on the prognostic role of PSCA expression, a tissue microarray containing 13,665 prostate cancers was… read more here.

Keywords: tumor; psca expression; prostate cancer; psca ... See more keywords
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Targeted alpha therapy with astatine-211-labeled anti-PSCA A11 minibody shows antitumor efficacy in prostate cancer xenografts and bone microtumors

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Published in 2020 at "EJNMMI Research"

DOI: 10.1186/s13550-020-0600-z

Abstract: Purpose Targeted alpha therapy (TAT) is a promising treatment for micrometastatic and minimal residual cancer. We evaluated systemic α-radioimmunotherapy (α-RIT) of metastatic castration-resistant prostate cancer (mCRPC) using the α-particle emitter 211 At-labeled to the anti-PSCA… read more here.

Keywords: 211 labeled; labeled anti; prostate cancer; psca ... See more keywords
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Ligand-inducible, prostate stem cell antigen (PSCA)-directed GoCAR-T cells in advanced solid tumors: Preliminary results with cyclophosphamide (Cy) ± fludarabine (Flu) lymphodepletion (LD).

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Published in 2019 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2019.37.15_suppl.2536

Abstract: 2536 Background: Cell-surface protein PSCA is upregulated in many solid tumors and correlates with disease stage. BPX-601, an autologous T-cell product expressing a PSCA-CD3ζ CAR and a rimiducid (Rim)-inducible MyD88/CD40 co-activation switch to augment T-cell… read more here.

Keywords: bpx 601; 601 rim; flu; cell ... See more keywords
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Ligand-inducible, prostate stem cell antigen (PSCA)-directed GoCAR-T cells in advanced solid tumors: Preliminary results from a dose escalation.

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Published in 2019 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2019.37.4_suppl.283

Abstract: 283 Background: PSCA, a cell surface protein, is upregulated in many solid tumors and correlates with disease stage. BPX601 is an autologous, T-cell product engineered to contain a PSCA-CD3ζ CAR plus the small molecule rimiducid… read more here.

Keywords: cell dose; dose escalation; solid tumors; cell ... See more keywords
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Development and Functional Characterization of a Versatile Radio-/Immunotheranostic Tool for Prostate Cancer Management

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14081996

Abstract: Simple Summary In previous studies, we described a modular Chimeric Antigen Receptor (CAR) T cell platform which we termed UniCAR. In contrast to conventional CARs, the interaction of UniCAR T cells does not occur directly… read more here.

Keywords: cell; anti psca; psca; psca igg4 ... See more keywords
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SNP rs2920280 in PSCA Is Associated with Susceptibility to Gastric Mucosal Atrophy and Is a Promising Biomarker in Japanese Individuals with Helicobacter pylori Infection

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Published in 2022 at "Diagnostics"

DOI: 10.3390/diagnostics12081988

Abstract: Helicobacter pylori infection results in gastric cancer (GC) with gastric mucosal atrophy (GMA). Some single-nucleotide polymorphisms (SNPs) in the prostate stem cell antigen gene (PSCA) are associated with GC and duodenal ulcers. However, the relationship… read more here.

Keywords: pylori infection; gma; rs2920280; susceptibility ... See more keywords