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Silencing Intersectin 1 Slows Orthotopic Neuroblastoma Growth in Mice

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Published in 2017 at "Journal of Pediatric Hematology/Oncology"

DOI: 10.1097/mph.0000000000000931

Abstract: Neuroblastoma accounts for 15% of all pediatric cancer deaths. Intersectin 1 (ITSN1), a scaffold protein involved in phosphoinositide 3-kinase (PI3K) signaling, regulates neuroblastoma cells independent of MYCN status. We hypothesize that by silencing ITSN1 in… read more here.

Keywords: pscr; orthotopic neuroblastoma; growth; neuroblastoma cells ... See more keywords