Pseudo-allergic compounds screened from Shengmai Injection by using high-expression Mas-related G protein-coupled receptor X2 cell membrane chromatography online coupled with liquid chromatography and mass spectrometry.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of separation science"
DOI: 10.1002/jssc.202001163
Abstract: Adverse drug reactions of Traditional Chinese medicine injection mainly manifested as pseudo-allergic reactions. In the present study, ginsenoside Rd, Ro and Rg3 were identified as pseudo-allergic components in Shengmai Injection by a high-expression Mas-related G… read more here.
Keywords: chromatography; mas related; shengmai injection; pseudo allergic ... See more keywords
Dehydroandrographolide targets CD300f and negatively regulated MRGPRX2‐induced pseudo‐allergic reaction
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DOI: 10.1002/ptr.7445
Abstract: Mas‐related G protein‐coupled receptor X2 (MRGPRX2) mediates mast cells (MCs) activation, which is a key target for the treatment of allergic diseases. However, there are few drugs targeting MRGPRX2. Leukocyte mono‐immunoglobulin‐like receptor 3 (CD300f) is… read more here.
Keywords: negatively regulated; pseudo allergic; regulated mrgprx2; mrgprx2 ... See more keywords
Shuxuening injection, derived from Ginkgo biloba leaf, induced pseudo-allergic reactions through hyperactivation of mTOR
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DOI: 10.1080/13880209.2020.1784238
Abstract: Abstract Context Shuxuening injection (SXNI), derived from the leaf of Ginkgo biloba L. (Ginkgoaceae), is widely used to treat cardio-cerebral vascular system related disease due to the efficacy of dilating the blood vessels and improving… read more here.
Keywords: ginkgo biloba; shuxuening injection; sxni; pseudo allergic ... See more keywords
Crosstalk between AdipoR1/AdipoR2 and Nrf2/HO‐1 signal pathways activated by β‐caryophyllene suppressed the compound 48/80 induced pseudo‐allergic reactions
Sign Up to like & getrecommendations! Published in 2021 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13555
Abstract: Mast cell activation is initiated by two signalling pathways: immunoglobulin E (IgE)‐dependent and IgE‐independent pathway. It is reported that the IgE‐independent type or pseudo‐allergy pathway gets activated by G‐protein‐dependent activation of the mast cell. Recently,… read more here.
Keywords: adipor1 adipor2; adipor2 nrf2; pseudo allergic; mast cell ... See more keywords