Semiparametric pseudo-score and pseudo-likelihood for evaluating correlate of protection in vaccine trials.
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DOI: 10.1002/sim.9807
Abstract: In vaccine clinical trials, vaccine efficacy endpoint analysis is usually associated with in high cost or extended study duration, due to the generally low infection rate. Correlate of protection (CoP), which refers to surrogate endpoint,… read more here.
Keywords: pseudo score; correlate protection; pseudo; pseudo likelihood ... See more keywords
Fast and highly efficient pseudo-likelihood methodology for large and complex ordinal data
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DOI: 10.1177/0962280215608213
Abstract: In longitudinal studies, continuous, binary, categorical, and survival outcomes are often jointly collected, possibly with some observations missing. However, when it comes to modeling responses, the ordinal ones have received less attention in the literature.… read more here.
Keywords: methodology; model; pseudo likelihood; likelihood methodology ... See more keywords
Doubly robust pseudo-likelihood for incomplete hierarchical binary data
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DOI: 10.1177/1471082x18808611
Abstract: Missing data is almost inevitable in correlated-data studies. For non-Gaussian outcomes with moderate to large sequences, direct-likelihood methods can involve complex, hard-to-manipulate likelihoods. Popular alternative approaches, like generalized estimating equations, that are frequently used to… read more here.
Keywords: hierarchical binary; robust pseudo; pseudo likelihood; binary data ... See more keywords