Semiparametric pseudo-score and pseudo-likelihood for evaluating correlate of protection in vaccine trials.
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DOI: 10.1002/sim.9807
Abstract: In vaccine clinical trials, vaccine efficacy endpoint analysis is usually associated with in high cost or extended study duration, due to the generally low infection rate. Correlate of protection (CoP), which refers to surrogate endpoint,… read more here.
Keywords: pseudo score; correlate protection; pseudo; pseudo likelihood ... See more keywords
EM estimation of the B-spline copula with penalized pseudo-likelihood functions
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DOI: 10.1007/s00362-024-01647-w
Abstract: The B-spline copula function is defined by a linear combination of elements of the normalized B-spline basis. We develop a modified EM algorithm, to maximize the penalized pseudo-likelihood function, wherein we use the smoothly clipped… read more here.
Keywords: pseudo likelihood; spline copula; estimation spline; penalized pseudo ... See more keywords
Fast and highly efficient pseudo-likelihood methodology for large and complex ordinal data
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DOI: 10.1177/0962280215608213
Abstract: In longitudinal studies, continuous, binary, categorical, and survival outcomes are often jointly collected, possibly with some observations missing. However, when it comes to modeling responses, the ordinal ones have received less attention in the literature.… read more here.
Keywords: methodology; model; pseudo likelihood; likelihood methodology ... See more keywords
Doubly robust pseudo-likelihood for incomplete hierarchical binary data
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DOI: 10.1177/1471082x18808611
Abstract: Missing data is almost inevitable in correlated-data studies. For non-Gaussian outcomes with moderate to large sequences, direct-likelihood methods can involve complex, hard-to-manipulate likelihoods. Popular alternative approaches, like generalized estimating equations, that are frequently used to… read more here.
Keywords: hierarchical binary; robust pseudo; pseudo likelihood; binary data ... See more keywords
Maximum Pseudo-Likelihood Estimation of Copula Models and Moments of Order Statistics
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DOI: 10.3390/risks12010015
Abstract: It has been shown that, despite being consistent and in some cases efficient, maximum pseudo-likelihood (MPL) estimation for copula models overestimates the level of dependence, especially for small samples with a low level of dependence.… read more here.
Keywords: pseudo likelihood; order statistics; copula models; estimation copula ... See more keywords