Is pseudoexfoliation glaucoma a neurodegenerative disorder?
Sign Up to like & getrecommendations! Published in 2021 at "Journal of biosciences"
DOI: 10.1007/s12038-021-00217-8
Abstract: Pseudoexfoliation (PEX) is a systemic age-related progressive disorder with ocular manifestations. The earlier stage of the disease, pseudoexfoliation syndrome (PEXS) involves deposition of white fibrillar aggregates on anterior and posterior eye tissues. It is also… read more here.
Keywords: pex; disorder; neurodegenerative disorder; pseudoexfoliation glaucoma ... See more keywords
Altered unfolded protein response and proteasome impairment in pseudoexfoliation pathogenesis
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Eye Research"
DOI: 10.1016/j.exer.2019.02.004
Abstract: ABSTRACT Pseudoexfoliation (PEX), an ocular disorder involving deposition of proteinaceous fibrils on the surface of anterior eye tissues, is a major contributing factor to worldwide glaucoma. Excessive production and accumulation of fibrillar materials in PEX… read more here.
Keywords: pex; response; unfolded protein; expression ... See more keywords
Significant lifespan difference between primary open-angle glaucoma and pseudoexfoliation glaucoma
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DOI: 10.1016/j.heliyon.2021.e06421
Abstract: Purpose Open-angle glaucoma (OAG) is a collective term for various subgroups of glaucoma of which primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PEG) are the most common. There is increasing evidence that both conditions have… read more here.
Keywords: death; angle glaucoma; glaucoma; open angle ... See more keywords
Genetic variants and haplotypes in fibulin-5 (FBLN5) are associated with pseudoexfoliation glaucoma but not with pseudoexfoliation syndrome
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DOI: 10.1042/bsr20221622
Abstract: Abstract Pseudoexfoliation (PEX) is a multifactorial age-related disease involving deposition of extracellular proteinaceous aggregates on anterior ocular tissues. The present study aims to identify functional variants in fibulin-5 (FBLN5) as risk factors for the development… read more here.
Keywords: fibulin fbln5; genetic variants; risk; pseudoexfoliation ... See more keywords
Peripapillary and Macular Vessel Density Measurement by Optical Coherence Tomography Angiography in Pseudoexfoliation and Primary Open-angle Glaucoma
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Glaucoma"
DOI: 10.1097/ijg.0000000000001464
Abstract: Supplemental Digital Content is available in the text. Precis: Pseudoexfoliation glaucoma eyes had a similar level of peripapillary and superficial macular vessel densities compared with primary open-angle glaucoma eyes matched for age and glaucoma severity… read more here.
Keywords: pseudoexfoliation; primary open; glaucoma; vessel ... See more keywords
Prevalence of Pseudoexfoliation Glaucoma Risk–associated Variants Within Lysyl Oxidase–like 1 in an Irish Population
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Glaucoma"
DOI: 10.1097/ijg.0000000000001475
Abstract: Supplemental Digital Content is available in the text. Precis: High-risk alleles of risk-associated single-nucleotide polymorphisms (SNPs) within the lysyl oxidase-like 1 (LOXL1) gene are associated with pseudoexfoliation in patients recruited from an Irish population. Purpose:… read more here.
Keywords: pseudoexfoliation; irish population; risk associated; risk ... See more keywords
Pseudoexfoliation syndrome and relating factors in a rural Japanese population: the Kumejima Study
Sign Up to like & getrecommendations! Published in 2020 at "Acta Ophthalmologica"
DOI: 10.1111/aos.14396
Abstract: To report the prevalence of pseudoexfoliation (PEX) syndrome and glaucoma associated with PEX (PEX‐G) and their relating factors of them in a south‐western island of Japan. read more here.
Keywords: relating factors; syndrome relating; factors rural; rural japanese ... See more keywords
Descemet’s membrane detachment after Nd:YAG laser iridotomy in a patient with pseudoexfoliation
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2021-246071
Abstract: Laser peripheral iridotomy is a relatively safe and an effective treatment for pupillary block. Descemet’s membrane detachment (DMD) is an uncommon condition that occurs as a complication of intraocular surgery or after trauma. In this… read more here.
Keywords: membrane detachment; laser; pseudoexfoliation; detachment yag ... See more keywords
Lack of association between lysyl oxidase-like 1 polymorphism in pseudoexfoliation syndrome and pseudoexfoliation glaucoma in North Indian population
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Ophthalmology"
DOI: 10.1177/1120672118795405
Abstract: Introduction: Pseudoexfoliation syndrome is commonly associated with pseudoexfoliation glaucoma. The two nonsynonymous single-nucleotide polymorphisms rs1048661 (R141L) and rs3825942 (G153D) within exon 1 of LOXL1 gene have been found to confer risk of pseudoexfoliation syndrome and… read more here.
Keywords: single nucleotide; pseudoexfoliation syndrome; association; pseudoexfoliation glaucoma ... See more keywords
The Role of Oxidative Status in the Pathogenesis of Primary Open-Angle Glaucoma, Pseudoexfolyation Syndrome and Glaucoma
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Ophthalmology"
DOI: 10.1177/11206721221113199
Abstract: Purpose To investigate the role of oxidative stress and antioxidant system in the etiopathogenesis of pseudoexfoliation and progression of pseudoexfoliation syndrome to glaucoma. Material and method A total of 20 patients with pseudoexfoliation syndrome, 20… read more here.
Keywords: glaucoma; role oxidative; role; oxidative stress ... See more keywords
Light and electron microscopic features of preclinical pseudoexfoliation syndrome
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0282784
Abstract: Purpose This study sought to explore the features of the anterior lens capsule in patients with preclinical pseudoexfoliation syndrome (pPEX) via light microscopy (LM) and transmission electron microscopy (TEM). Design Cross-sectional, prospective, and observational case… read more here.
Keywords: lens capsules; syndrome; ppex; capsule ... See more keywords