Is pseudoexfoliation glaucoma a neurodegenerative disorder?
Sign Up to like & getrecommendations! Published in 2021 at "Journal of biosciences"
DOI: 10.1007/s12038-021-00217-8
Abstract: Pseudoexfoliation (PEX) is a systemic age-related progressive disorder with ocular manifestations. The earlier stage of the disease, pseudoexfoliation syndrome (PEXS) involves deposition of white fibrillar aggregates on anterior and posterior eye tissues. It is also… read more here.
Keywords: pex; disorder; neurodegenerative disorder; pseudoexfoliation glaucoma ... See more keywords
Surgical and laser interventions for pseudoexfoliation glaucoma systematic review of randomized controlled trials
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DOI: 10.1038/s41433-021-01424-1
Abstract: To assess the comparative effectiveness and safety of different surgical and laser techniques in people with pseudoexfoliation glaucoma (PXFG). We conducted a systematic review including randomized controlled trials (RCT) that compared any pair of surgical… read more here.
Keywords: randomized controlled; laser; systematic review; surgical laser ... See more keywords
Genetic variants and haplotypes in fibulin-5 (FBLN5) are associated with pseudoexfoliation glaucoma but not with pseudoexfoliation syndrome
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DOI: 10.1042/bsr20221622
Abstract: Abstract Pseudoexfoliation (PEX) is a multifactorial age-related disease involving deposition of extracellular proteinaceous aggregates on anterior ocular tissues. The present study aims to identify functional variants in fibulin-5 (FBLN5) as risk factors for the development… read more here.
Keywords: fibulin fbln5; genetic variants; risk; pseudoexfoliation ... See more keywords
Pseudoexfoliation Glaucoma as a Predictor of Refractive Surprise After Uneventful Cataract Surgery
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Glaucoma"
DOI: 10.1097/ijg.0000000000002187
Abstract: Précis: The pseudoexfoliation glaucoma group produced higher mean absolute error (MAE) and higher percentages of large-magnitude prediction error, in all investigated intraocular lens formulas. Postoperative anterior chamber angle and change in intraocular pressure (IOP) were… read more here.
Keywords: cataract surgery; glaucoma; error; barrett universal ... See more keywords
Lack of association between lysyl oxidase-like 1 polymorphism in pseudoexfoliation syndrome and pseudoexfoliation glaucoma in North Indian population
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Ophthalmology"
DOI: 10.1177/1120672118795405
Abstract: Introduction: Pseudoexfoliation syndrome is commonly associated with pseudoexfoliation glaucoma. The two nonsynonymous single-nucleotide polymorphisms rs1048661 (R141L) and rs3825942 (G153D) within exon 1 of LOXL1 gene have been found to confer risk of pseudoexfoliation syndrome and… read more here.
Keywords: single nucleotide; pseudoexfoliation syndrome; association; pseudoexfoliation glaucoma ... See more keywords
[Late results of phaco-canaloplasty in patients with concomitant advanced pseudoexfoliation glaucoma and cataract].
Sign Up to like & getrecommendations! Published in 2018 at "Vestnik oftalmologii"
DOI: 10.17116/oftalma2018134328
Abstract: PURPOSE To assess the safety and efficacy of phaco-canaloplasty in patients with concomitant advanced pseudoexfoliation glaucoma and cataract. MATERIAL AND METHODS The study included 56 patients (57 eyes) who underwent phacoanaloplasty guided by Glaucolight microcatheter.… read more here.
Keywords: advanced pseudoexfoliation; concomitant advanced; glaucoma; glaucoma cataract ... See more keywords
Evaluation of ABCA1 and FNDC3B Gene Polymorphisms Associated With Pseudoexfoliation Glaucoma and Primary Angle-Closure Glaucoma in a Saudi Cohort
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.877174
Abstract: Objective: It is plausible that common disease mechanisms exist in glaucoma pathophysiology. Accordingly, we investigated the genetic association of two previously reported primary open-angle glaucoma (POAG)-related gene polymorphisms, rs2472493 (A > G) in ABCA1 and… read more here.
Keywords: glaucoma; primary angle; gene polymorphisms; angle closure ... See more keywords
Global and Comparative Proteome Signatures in the Lens Capsule, Trabecular Meshwork, and Iris of Patients With Pseudoexfoliation Glaucoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.877250
Abstract: Pseudoexfoliation (PXF) is characterized by the accumulation of the exfoliative material in the eye and high rates of blindness if left untreated. Pseudoexfoliation glaucoma (PXG) is generally diagnosed too late due to its asymptomatic nature,… read more here.
Keywords: glaucoma; lens capsule; disease; trabecular meshwork ... See more keywords
Genome-Wide RNA Sequencing of Human Trabecular Meshwork Cells Treated with TGF-β1: Relevance to Pseudoexfoliation Glaucoma
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DOI: 10.3390/biom12111693
Abstract: Pseudoexfoliation glaucoma (XFG) is an aggressive form of secondary open angle glaucoma, characterised by the production of exfoliation material and is estimated to affect 30 million people worldwide. Activation of the TGF-β pathway by TGF-β1… read more here.
Keywords: rna; trabecular meshwork; pseudoexfoliation glaucoma; glaucoma ... See more keywords
Prevalence of risk alleles in the lysyl oxidase-like 1 gene in pseudoexfoliation glaucoma patients in India
Sign Up to like & getrecommendations! Published in 2022 at "Indian Journal of Ophthalmology"
DOI: 10.4103/ijo.ijo_2664_21
Abstract: Purpose: The purpose of this study was to genotype two previously identified SNPs (rs1048661:R141L, and rs3825942:G153D) in the lysyl oxidase-like 1 (LOXL1) gene and determine their association with pseudoexfoliation glaucoma (XFG) in patients from Pune,… read more here.
Keywords: oxidase like; lysyl oxidase; risk; risk alleles ... See more keywords
Commentary: Cataract versus combined surgery in pseudoexfoliation glaucoma
Sign Up to like & getrecommendations! Published in 2023 at "Indian Journal of Ophthalmology"
DOI: 10.4103/ijo.ijo_2933_22
Abstract: Glaucoma associated with exfoliation syndrome is particularly difficult to manage. It tends to be more aggressive and have a poorer prognosis than other open‐angle glaucomas.[1] The reasons for this may be associated with higher intraocular… read more here.
Keywords: glaucoma; versus combined; cataract versus; commentary cataract ... See more keywords