Pseudogene ACTBP2 increases blood–brain barrier permeability by promoting KHDRBS2 transcription through recruitment of KMT2D/WDR5 in Aβ1–42 microenvironment
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DOI: 10.1038/s41420-021-00531-y
Abstract: The blood–brain barrier (BBB) has a vital role in maintaining the homeostasis of the central nervous system (CNS). Changes in the structure and function of BBB can accelerate Alzheimer’s disease (AD) development. β-Amyloid (Aβ) deposition… read more here.
Keywords: microenvironment; khdrbs2 transcription; hey2; pseudogene actbp2 ... See more keywords