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   Articles with "pseudomallei" as a keyword



Burkholderia pseudomallei acquired ceftazidime resistance due to gene duplication and amplification.

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recommendations! Published in 2019 at "International journal of antimicrobial agents"

DOI: 10.1016/j.ijantimicag.2019.01.003

Abstract: Ceftazidime (CAZ) is the antibiotic of choice for the treatment of Burkholderia pseudomallei infection (melioidosis). The chromosomally-encoded PenA β-lactamase possesses weak cephalosporinase activity. The wild-type penA gene confers clinically significant CAZ resistance only when overexpressed… read more here.

Keywords: gene duplication; resistance; pseudomallei; gene ... See more keywords

Phylogenetic Diversity of Burkholderia pseudomallei isolated from veterinary cases and the environments in Peninsular Malaysia

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recommendations! Published in 2018 at "Veterinary and Animal Science"

DOI: 10.1016/j.vas.2018.07.004

Abstract: This study was designed to determine the genotype and the phylogeny of Burkholderia pseudomallei isolated from veterinary cases and from the animal environments in Peninsular Malaysia. The Malaysian B. pseudomallei population were then compared to… read more here.

Keywords: malaysia; pseudomallei isolated; veterinary cases; pseudomallei ... See more keywords

D-LL-31 in combination with ceftazidime synergistically enhances bactericidal activity and biofilm destruction in Burkholderia pseudomallei

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recommendations! Published in 2019 at "Biofouling"

DOI: 10.1080/08927014.2019.1632835

Abstract: Abstract Melioidosis is a severe disease caused by Burkholderia pseudomallei. The biofilm of B. pseudomallei acquires resistance to several antibiotics and may be related to relapse in melioidosis patients. Here, the killing activity of antimicrobial… read more here.

Keywords: burkholderia pseudomallei; ceftazidime synergistically; biofilm; pseudomallei ... See more keywords

Bactericidal and antibiofilm activities of Piper betle extract against Burkholderia pseudomallei: in vitro and in silico approaches

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recommendations! Published in 2024 at "Biofouling"

DOI: 10.1080/08927014.2024.2438689

Abstract: Abstract Burkholderia pseudomallei biofilm is a significant virulence factor in infection. This study aimed to investigate antibacterial and antibiofilm activities of Piper betle extract against B. pseudomallei. The MIC and MBC values of the extract… read more here.

Keywords: activities piper; antibiofilm activities; pseudomallei; betle extract ... See more keywords

Burkholderia pseudomallei BipD initiates mitophagy to evade killing by hijacking host KLHL9-KLHL13-CUL3 E3 ligase to ubiquitinate IMMT

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recommendations! Published in 2024 at "Autophagy"

DOI: 10.1080/15548627.2024.2403125

Abstract: ABSTRACT Burkholderia pseudomallei (B. pseudomallei) is a facultative intracellular parasitic pathogen with multiple immune escape mechanisms. Mitophagy is critical for mitochondrial quality control and function in various biological processes. We reported that B. pseudomallei infection… read more here.

Keywords: klhl9; ligase; host; pseudomallei ... See more keywords

Pathogenicity and virulence of Burkholderia pseudomallei

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recommendations! Published in 2022 at "Virulence"

DOI: 10.1080/21505594.2022.2139063

Abstract: ABSTRACT The soil saprophyte, Burkholderia pseudomallei, is the causative agent of melioidosis, a disease endemic in South East Asia and northern Australia. Exposure to B. pseudomallei by either inhalation or inoculation can lead to severe… read more here.

Keywords: cell; pseudomallei; burkholderia pseudomallei; virulence ... See more keywords
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Validation of a Lateral Flow Test for the Presumptive Identification of the Presence of Burkholderia mallei or Burkholderia pseudomallei in Environmental Samples.

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recommendations! Published in 2022 at "Health security"

DOI: 10.1089/hs.2021.0168

Abstract: We conducted a comprehensive, multiphase laboratory evaluation of InBios Active Melioidosis Detect (AMD) rapid test, a lateral flow immunoassay designed to detect capsular polysaccharides produced by Burkholderia mallei or Burkholderia pseudomallei, used in conjunction with… read more here.

Keywords: lateral flow; pseudomallei; test; burkholderia mallei ... See more keywords

Finafloxacin overcomes Burkholderia pseudomallei efflux-mediated fluoroquinolone resistance

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recommendations! Published in 2017 at "Journal of Antimicrobial Chemotherapy"

DOI: 10.1093/jac/dkw529

Abstract: Sir, Burkholderia pseudomallei is a biothreat agent and causes melioidosis, a globally emerging infectious disease with high case fatality rates, and B. pseudomallei infections are difficult to treat. Although curiously rare in B. pseudomallei, drug… read more here.

Keywords: finafloxacin; bpeef oprc; resistance; pseudomallei ... See more keywords
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Epidemiological and Clinical Characteristics of Melioidosis Caused by Gentamicin-Susceptible Burkholderia pseudomallei in Sarawak, Malaysia

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recommendations! Published in 2021 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofab460

Abstract: Abstract Background Burkholderia pseudomallei, the causative agent of melioidosis, is intrinsically resistant to a broad range of antibiotics, including aminoglycosides. In Sarawak, Malaysia, a high proportion of melioidosis cases are caused by gentamicin-susceptible isolates. There… read more here.

Keywords: gentamicin susceptible; pseudomallei; sarawak malaysia; melioidosis ... See more keywords

Misidentification of Burkholderia pseudomallei as Acinetobacter species in northern Thailand

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recommendations! Published in 2019 at "Transactions of the Royal Society of Tropical Medicine and Hygiene"

DOI: 10.1093/trstmh/try108

Abstract: Abstract Background Burkholderia pseudomallei is the causative agent of melioidosis, a disease endemic throughout the tropics. Methods A study of reported Acinetobacter spp. bacteraemia was performed at Chiang Rai provincial hospital from 2014 to 2015.… read more here.

Keywords: acinetobacter spp; pseudomallei; misidentification burkholderia; burkholderia pseudomallei ... See more keywords

Melioidosis and Burkholderia pseudomallei: progress in epidemiology, diagnosis, treatment and vaccination

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recommendations! Published in 2022 at "Current Opinion in Infectious Diseases"

DOI: 10.1097/qco.0000000000000869

Abstract: Purpose of review Melioidosis and its causative bacterium Burkholderia pseudomallei are being found in unexpected locations and bacterial genotyping is providing new insights into global spread and where and how individuals are being infected. This… read more here.

Keywords: pseudomallei; diagnosis treatment; epidemiology; melioidosis ... See more keywords