Targeted Genetic Sequencing Analysis of 223 Cases of Pseudomyxoma Peritonei Treated by Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Shows Survival Related to GNAS and KRAS Status
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DOI: 10.1002/cam4.70340
Abstract: Pseudomyxoma peritonei (PMP) is an unusual condition with unique behaviour caused by a mucinous neoplasm, usually arising from the appendix. The aim of this study was to evaluate the prevalence of genomic alterations in clinical… read more here.
Keywords: targeted genetic; peritonei; genetic sequencing; analysis 223 ... See more keywords
Prognostic significance of the presence of epithelial cell clusters in the ascites of patients with pseudomyxoma peritonei
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DOI: 10.1002/dc.24262
Abstract: Pseudomyxoma peritonei (PMP) is a rare condition characterized by intraperitoneal accumulation of mucus due to mucinous neoplasia. The characteristic cytological feature of PMP in the ascites is abundant mucus with or without epithelial cell clusters.… read more here.
Keywords: epithelial cell; cell clusters; prognostic significance; pseudomyxoma peritonei ... See more keywords
The mutational landscape and prognostic indicators of pseudomyxoma peritonei originating from the ovary
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DOI: 10.1002/ijc.33460
Abstract: Pseudomyxoma peritonei (PMP) is a rare disorder with unique pathological and genetic changes. Although several studies have reported the clinical features and mutational changes of PMP that originates from the appendix, few studies on PMP… read more here.
Keywords: mutational landscape; originating ovary; pseudomyxoma peritonei; landscape ... See more keywords
New insights in the management of pseudomyxoma peritonei
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DOI: 10.1002/jso.27842
Abstract: While a rare entity, peritoneal pseudomyxoma treatment evolves. Decision‐making criteria improve with imaging development and exploratory laparoscopy. Surgery remains at the core of the therapeutic strategy whatever disease progression. Complete cytoreduction plus hyperthermic intraperitoneal chemotherapy… read more here.
Keywords: pseudomyxoma; management pseudomyxoma; new insights; insights management ... See more keywords
A combinatorial culture strategy to develop pseudomyxoma peritonei organoid models
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DOI: 10.1002/jso.27850
Abstract: Few preclinical models of pseudomyxoma peritonei (PMP) have been developed, probably due to the tumor's low incidence and its peculiar characteristics of slow growth. Therefore, there is a need to develop more refined PMP models… read more here.
Keywords: culture strategy; culture; combinatorial culture; organoid models ... See more keywords
Impact of a modified peritoneal cancer index using FDG-PET/CT (PET-PCI) in predicting tumor grade and progression-free survival in patients with pseudomyxoma peritonei
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DOI: 10.1007/s00330-019-06102-1
Abstract: ObjectivesThe peritoneal cancer index (PCI) is widely used for assessing pseudomyxoma peritonei (PMP) in surgery. The aim of this study was to evaluate the utility of a modified PCI using 18F-fluorodeoxyglucose (18F-FDG)-PET/CT (PET-PCI) for predicting… read more here.
Keywords: pet; pet pci; pseudomyxoma peritonei; fdg pet ... See more keywords
The biological basis and function of GNAS mutation in pseudomyxoma peritonei: a review
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DOI: 10.1007/s00432-020-03321-8
Abstract: Pseudomyxoma peritonei (PMP) is a rare clinical malignancy syndrome characterized by the uncontrollable accumulation of copious mucinous ascites in the peritoneal cavity, resulting in “jelly belly”. The mechanism of tumor progression and mucin hypersecretion remains… read more here.
Keywords: pseudomyxoma peritonei; review; mutation; gnas mutation ... See more keywords
Efficacy of modified FOLFOX6 chemotherapy for patients with unresectable pseudomyxoma peritonei
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DOI: 10.1007/s10147-019-01592-x
Abstract: Background Pseudomyxoma peritonei (PMP) is a rare malignancy, and there is insufficient evidence about systemic chemotherapy for this disease. Methods We retrospectively evaluated the efficacy and safety of a chemotherapeutic regimen with 5-fluorouracil and oxaliplatin… read more here.
Keywords: pseudomyxoma peritonei; modified folfox6; unresectable pseudomyxoma; patients unresectable ... See more keywords
Pseudomyxoma Peritonei: Case Report and Literature Review
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DOI: 10.1007/s12029-018-00192-8
Abstract: Pseudomyxoma peritonei (PMP) is a disorder characterized by an intra-abdominal accumulation of mucin secondary to the growth of neoplastic mucin-secreting cells on peritoneal surfaces [1, 2]. PMP is a rare condition with an estimated incidence… read more here.
Keywords: pseudomyxoma; mucinous adenocarcinoma; pseudomyxoma peritonei; high grade ... See more keywords
Primary Mucinous Cystadenocarcinoma of Spleen with Pseudomyxoma Peritonei: a Very Rare Entity
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DOI: 10.1007/s12262-019-01978-1
Abstract: Primary mucinous cystadenocarcinoma of the spleen is an extremely rare tumour. Only 7 cases have been reported in the literature. Mucinous cystadenocarcinoma of the spleen presenting as pseudomyxoma peritonei has been reported only once. Our… read more here.
Keywords: mucinous cystadenocarcinoma; pseudomyxoma peritonei; cystadenocarcinoma spleen; primary mucinous ... See more keywords
Progression to pseudomyxoma peritonei in patients with low grade appendiceal mucinous neoplasms discovered at time of appendectomy.
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DOI: 10.1016/j.amjsurg.2021.12.003
Abstract: BACKGROUND The discovery of a low grade appendiceal mucinous neoplasm (LAMN) during appendectomy is a rare scenario. These neoplasms can progress to pseudomyxoma peritonei (PMP), however the incidence of progression is not well known. METHODS… read more here.
Keywords: appendiceal; appendiceal mucinous; grade appendiceal; pseudomyxoma peritonei ... See more keywords