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Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9057-3_8
Abstract: In many single-cell RNA-seq (scRNA-seq) experiments, cells represent progressively changing states along a continuous biological process. A useful approach to analyzing data from such experiments is to computationally order cells based on their gradual transition…
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Keywords:
reconstruction;
seq;
pseudotime;
reconstruction using ... See more keywords
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Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac670
Abstract: MOTIVATION The emerging single-cell Hi-C technology provides opportunities to study dynamics of chromosomal organization. How to construct a pseudotime path using single-cell Hi-C contact matrices to order cells along developmental trajectory is a challenging topic,…
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Keywords:
cell;
pseudotime;
schicptr unsupervised;
graph refinement ... See more keywords
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Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.828505
Abstract: Introduction As the molecular features of lung adenocarcinoma (LUAD) have been evaluated as a cross-sectional study, the course of tumor characteristics has not been modeled. The temporal evolution of the tumor immune microenvironment (TIME), as…
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Keywords:
cell;
pseudotime;
lung adenocarcinoma;
clinico molecular ... See more keywords