Interferon inducible pseudouridine modification in human mRNA by quantitative nanopore profiling
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DOI: 10.1186/s13059-021-02557-y
Abstract: Pseudouridine (Ψ) is an abundant mRNA modification in mammalian transcriptome, but its functions have remained elusive due to the difficulty of transcriptome-wide mapping. We develop a nanopore native RNA sequencing method for quantitative Ψ prediction… read more here.
Keywords: pseudouridine modification; interferon inducible; inducible pseudouridine; pseudouridine ... See more keywords
Gene Expression-Based Predication of RNA Pseudouridine Modification in Tumor Microenvironment and Prognosis of Glioma Patients
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.727595
Abstract: Aberrant expression of methyltransferases and demethylases may augment tumor initiation, proliferation and metastasis through RNA modification, such as m6A and m5C. However, activity of pseudouridine (Ψ) modification of RNA remains unknown in glioma, the most… read more here.
Keywords: tumor; expression; prognosis; glioma ... See more keywords