Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect pre-mRNA processing.
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DOI: 10.1016/j.molcel.2021.12.023
Abstract: Pseudouridine is a modified nucleotide that is prevalent in human mRNAs and is dynamically regulated. Here, we investigate when in their life cycle mRNAs become pseudouridylated to illuminate the potential regulatory functions of endogenous mRNA… read more here.
Keywords: pseudouridine synthases; pre; mrna processing; pre mrna ... See more keywords
Integrative multiomics evaluation reveals the importance of pseudouridine synthases in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.944681
Abstract: Background: The pseudouridine synthases (PUSs) have been reported to be associated with cancers. However, their involvement in hepatocellular carcinoma (HCC) has not been well documented. Here, we assess the roles of PUSs in HCC. Methods:… read more here.
Keywords: pseudouridine synthases; hepatocellular carcinoma; hcc; expression ... See more keywords