Genomic RNA Binding Promotes Retroviral Gag Protein Interactions in an Assembly-Competent Conformation Leading to Selective Genome Packaging
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DOI: 10.1016/j.bpj.2016.11.1699
Abstract: In HIV-1 infected cells, full-length viral genomic RNA (gRNA) is selectively packaged by the HIV-1 Gag protein despite a vast excess of spliced viral and host RNAs. The mechanism of this selective packaging is incompletely… read more here.
Keywords: psi rna; gag; rna; genomic rna ... See more keywords