Pharmacokinetic modeling of PSMA targeted nanobubbles for quantification of extravasation and binding in mice models of prostate cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Medical physics"
DOI: 10.1002/mp.15962
Abstract: PURPOSE Contrast-enhanced ultrasound (CEUS) by injection of microbubbles (MBs) has shown promise as a cost-effective imaging modality for prostate cancer (PCa) detection. More recently, nanobubbles (NBs) have been proposed as novel ultrasound contrast agents. Unlike… read more here.
Keywords: mice models; prostate cancer; cancer; psma targeted ... See more keywords
Pearls and pitfalls in clinical interpretation of prostate-specific membrane antigen (PSMA)-targeted PET imaging
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-017-3780-7
Abstract: BackgroundThe rapidly expanding clinical adaptation of prostate-specific membrane antigen (PSMA)-targeted PET imaging in the evaluation of patients with prostate cancer has placed an increasing onus on understanding both the potential pearls of interpretation as well… read more here.
Keywords: prostate specific; pet imaging; psma targeted; specific membrane ... See more keywords
Organ and tumour dosimetry of 177Lu-rhPSMA-10.1, a novel PSMA-targeted therapy: results from a Phase I trial
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-025-07313-z
Abstract: To evaluate tumour and normal organ dosimetry of PSMA-targeted RLT 177Lu-rhPSMA-10.1. PSMA-positive mCRPC patients experiencing disease progression following standard-of-care treatment were enrolled and underwent ≤ 3 cycles of 5.55 or 7.40 GBq 177Lu-rhPSMA-10.1 at 6-week intervals. Multi-bed… read more here.
Keywords: rhpsma; 177lu rhpsma; psma targeted; anatomy ... See more keywords
Letter to the Editor re: Semiquantitative Parameters in PSMA-Targeted PET Imaging with [18F]DCFPyL: Impact of Tumor Burden on Normal Organ Uptake
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Imaging and Biology"
DOI: 10.1007/s11307-019-01438-y
Abstract: Letter to the Editor re: Semiquantitative Parameters in PSMA-Targeted PET Imaging with [F]DCFPyL: Impact of Tumor Burden on Normal Organ Uptake M. C. F. Cysouw , B. H. E. Jansen, M. Yaqub, J. Voortman, A.… read more here.
Keywords: amsterdam; psma targeted; semiquantitative parameters; editor semiquantitative ... See more keywords
Patterns of uptake of prostate-specific membrane antigen (PSMA)-targeted 18F-DCFPyL in peripheral ganglia
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Nuclear Medicine"
DOI: 10.1007/s12149-017-1201-4
Abstract: ObjectiveRadiotracers targeting prostate-specific membrane antigen (PSMA) have increasingly been recognized as showing uptake in a number of normal structures, anatomic variants, and non-prostate-cancer pathologies. We aimed to explore the frequency and degree of uptake in… read more here.
Keywords: ganglia; 18f dcfpyl; prostate specific; psma targeted ... See more keywords
PSMA-targeted [18F]DCFPyL PET/CT-avid lesions in a patient with prostate cancer: Clinical decision-making informed by the PSMA-RADS interpretive framework
Sign Up to like & getrecommendations! Published in 2019 at "Urology Case Reports"
DOI: 10.1016/j.eucr.2019.01.007
Abstract: We present the case of a man with oligometastatic prostate cancer who underwent a PSMA-targeted 18F-DCFPyL PET/CT scan in order to illustrate how the PSMA-RADS grading sytem can be successfully used to support clinical decision-making… read more here.
Keywords: 18f dcfpyl; prostate cancer; targeted 18f; psma targeted ... See more keywords
Prostate Cancer Local Recurrence Detected With Both 18F-Fluciclovine and PSMA-targeted 18F-DCFPyL PET/CT.
Sign Up to like & getrecommendations! Published in 2017 at "Urology"
DOI: 10.1016/j.urology.2017.06.015
Abstract: We present the case of a 79-year-old man with an elevated postprostatectomy prostate-specific antigen level who was sequentially imaged with positron emission tomography/computed tomography (PET/CT) using 18F-fluciclovine followed by PSMA-targeted 18F-DCFPyL. Although both imaging tests… read more here.
Keywords: prostate; 18f dcfpyl; prostate cancer; targeted 18f ... See more keywords
Development of a Novel Engineered Antibody Format for PSMA-Targeted Radionuclide Therapy
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.4c01193
Abstract: Prostate cancer remains a prevalent and lethal malignancy across the globe. Despite ongoing advances in therapeutic approaches, these remain ineffective, and new treatments are drastically needed. Prostate-specific membrane antigen (PSMA)-targeted radionuclide therapy is a well-developed… read more here.
Keywords: radionuclide therapy; antibody; psma targeted; psma ... See more keywords
In Vitro and In Vivo Study of Novel PSMA-Targeted Radioligands: Enhancing Tumor Uptake and Therapeutic Efficacy through Zwitterionization and Albumin-Binding Strategies.
Sign Up to like & getrecommendations! Published in 2025 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.5c00214
Abstract: Prostate-specific membrane antigen (PSMA) targeted radioligand therapy (TRT) for metastatic castration-resistant prostate cancer has demonstrated significant potential. This study aimed to develop an optimal radiotherapeutic agent suitable for high-level PSMA expression by optimizing the ligand… read more here.
Keywords: tumor uptake; psma targeted; albumin binding; psma ... See more keywords
PSMA-targeted arsenic nanosheets: a platform for prostate cancer therapy via ferroptosis and ATM deficiency-triggered chemosensitization.
Sign Up to like & getrecommendations! Published in 2021 at "Materials horizons"
DOI: 10.1039/d0mh01992e
Abstract: Ferroptosis, a newly recognized form of non-apoptotic cell death, has recently been introduced for effective cancer therapy. The reported ferroptosis-inducing nanomaterials mainly consisted of metal-based components. Herein, we designed an inorganic metal-free nanoplatform, PSMA-targeted arsenic… read more here.
Keywords: psma targeted; cancer; prostate cancer; ferroptosis ... See more keywords
Prostate-Specific Membrane Antigen (PSMA)-Targeted PET Imaging of Prostate Cancer: An Update on Important Pitfalls.
Sign Up to like & getrecommendations! Published in 2019 at "Seminars in nuclear medicine"
DOI: 10.1053/j.semnuclmed.2019.02.006
Abstract: The continuing adoption of prostate specific membrane antigen (PSMA)-targeted PET for prostate cancer molecular imaging requires imagers and clinicians alike to be aware of the increasing number of potential interpretive pitfalls that have been reported.… read more here.
Keywords: targeted pet; prostate cancer; psma; psma targeted ... See more keywords