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Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.00611-22
Abstract: HBx is a multifunctional viral oncoprotein that plays an essential role in the viral life cycle and hepatocarcinogenesis. HBx degradation occurs through the ubiquitin-proteasome system (UPS). ABSTRACT Hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) is…
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Keywords:
ubiquitin independent;
26s proteasome;
hbx;
psmc3 ... See more keywords
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Published in 2020 at "EMBO Molecular Medicine"
DOI: 10.15252/emmm.201911861
Abstract: The ubiquitin–proteasome system degrades ubiquitin‐modified proteins to maintain protein homeostasis and to control signalling. Whole‐genome sequencing of patients with severe deafness and early‐onset cataracts as part of a neurological, sensorial and cutaneous novel syndrome identified…
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Keywords:
proteasome subunit;
proteotoxic stress;
psmc3;