Koebner phenomenon leading to the formation of new psoriatic lesions: evidences and mechanisms
Sign Up to like & getrecommendations! Published in 2019 at "Bioscience Reports"
DOI: 10.1042/bsr20193266
Abstract: Abstract Koebner phenomenon refers to the emergence of new psoriatic lesions in the healthy skin regions following an injury/trauma to psoriatic patients. The occurrence of psoriatic lesions at unusual areas of the body regions such… read more here.
Keywords: koebner phenomenon; development new; new psoriatic; psoriatic lesions ... See more keywords
FAM3C/ILEI protein is elevated in psoriatic lesions and triggers psoriasiform hyperproliferation in mice.
Sign Up to like & getrecommendations! Published in 2023 at "EMBO molecular medicine"
DOI: 10.15252/emmm.202216758
Abstract: FAM3C/ILEI is an important cytokine for tumor progression and metastasis. However, its involvement in inflammation remains elusive. Here, we show that ILEI protein is highly expressed in psoriatic lesions. Inducible keratinocyte-specific ILEI overexpression in mice… read more here.
Keywords: fam3c ilei; psoriatic lesions; mice; ilei protein ... See more keywords
Hypomethylation of HLA-DRB1 and its clinical significance in psoriasis
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DOI: 10.18632/oncotarget.12468
Abstract: Increasing evidences indicate that the abnormal DNA methylation is involved in the pathogenesis of psoriasis. A number of SNPs in HLA-DRB1 have been found being associated with the risk of psoriasis, however it is unclear… read more here.
Keywords: methylation; psoriatic lesions; hla drb1; hla ... See more keywords