Xenotransplantation Model of Psoriasis.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6786-5_7
Abstract: Psoriasis is a chronic autoimmune skin disease affecting approximately 2 % of the population with a major psychosocial and socioeconomic impact. A causal therapy leading to permanent cure is not available, and current treatments only… read more here.
Keywords: psoriasis; psoriasis xenotransplantation; model; psoriatic skin ... See more keywords
Development of a 3D psoriatic skin model optimized for infiltration of IL-17A producing T cells: focus on the crosstalk between T cells and psoriatic keratinocytes.
Sign Up to like & getrecommendations! Published in 2021 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2021.09.018
Abstract: Psoriasis is a chronic inflammatory skin disease involving several cell types, including T cells, via the IL-23/IL-17 axis. IL-17A acts on the surrounding epithelial cells thus resulting in an inflammatory feedback loop. The development of… read more here.
Keywords: psoriatic skin; model; cells psoriatic; skin model ... See more keywords
Microneedle and Iontophoresis Mediated Delivery of Methotrexate into and across Healthy and Psoriatic Skin.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2022.121693
Abstract: Psoriasis is a condition of the skin which involves scales, dry patches, and inflammation. Methotrexate (logP: -1.8, MW:454.44g/mol) is administered orally or intravenously to treat psoriasis. The first-pass metabolism and systemic toxicity can be avoided… read more here.
Keywords: delivery; healthy psoriatic; delivery methotrexate; psoriatic skin ... See more keywords
Transcriptional landscape of human endogenous retroviruses (HERVs) and other repetitive elements in psoriatic skin
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-22734-7
Abstract: Human endogenous retrovirus (HERV) sequences make up at least 8% of the human genome. Transcripts originating from these loci as well as proteins encoded by them have been detected in various tissues. HERVs are believed… read more here.
Keywords: psoriatic skin; hervs repetitive; transcriptional landscape; repetitive elements ... See more keywords
Psoriatic skin inflammation is promoted by c‐Jun/AP‐1‐dependent CCL2 and IL‐23 expression in dendritic cells
Sign Up to like & getrecommendations! Published in 2021 at "EMBO Molecular Medicine"
DOI: 10.15252/emmm.202012409
Abstract: Toll‐like receptor (TLR) stimulation induces innate immune responses involved in many inflammatory disorders including psoriasis. Although activation of the AP‐1 transcription factor complex is common in TLR signaling, the specific involvement and induced targets remain… read more here.
Keywords: dcs; psoriatic skin; jun; ccl2 ... See more keywords
Effects of nanoparticles with hydrotropic nicotinamide on tacrolimus: permeability through psoriatic skin and antipsoriatic and antiproliferative activities
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s126210
Abstract: The hybrid system based on nanoparticles (NPs) self-assembled by the conjugations of hyaluronic acid with cholesterol (HA–Chol NPs) combined with nicotinamide (NIC) for tacrolimus (FK506), ie, FK506 NPs–NIC, has been confirmed to exhibit a significant… read more here.
Keywords: fk506; chol nps; nps nic; psoriatic skin ... See more keywords
Psoriatic Skin Lesions after Apalutamide Treatment
Sign Up to like & getrecommendations! Published in 2022 at "Acta Dermato-Venereologica"
DOI: 10.2340/actadv.v102.858
Abstract: Abstract is missing (Short communication) read more here.
Keywords: lesions apalutamide; apalutamide treatment; skin lesions; psoriatic skin ... See more keywords
Remodeling of the Dermal Extracellular Matrix in a Tissue-Engineered Psoriatic Skin Model by n-3 Polyunsaturated Fatty Acids
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10051078
Abstract: Psoriasis is an inflammatory skin disease mainly associated with an epidermal disorder. However, the involvement of the dermal extracellular matrix (ECM) composition in psoriasis is still poorly understood. This study aimed to investigate the expression… read more here.
Keywords: extracellular matrix; skin; dermal extracellular; polyunsaturated fatty ... See more keywords