Association of MAPT Subhaplotypes With Risk of Progressive Supranuclear Palsy and Severity of Tau Pathology.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2019.0250
Abstract: Importance The association between the microtubule-associated protein tau (MAPT) H1 haplotype and the risk of progressive supranuclear palsy (PSP) has been well documented. However, the specific H1 subhaplotypes that drive the association have not been… read more here.
Keywords: risk; psp; tau pathology; pathology ... See more keywords
Self‐Sacrificially Degradable Pseudo‐Semiconducting Polymer Nanoparticles that Integrate NIR‐II Fluorescence Bioimaging, Photodynamic Immunotherapy, and Photo‐Activated Chemotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202203820
Abstract: Semiconducting polymers (SP) hold great promise for cancer phototherapy due to their excellent optical properties; however, their clinical application is still hampered by their poor biodegradability. Herein, a self‐sacrificially biodegradable pseudo‐semiconducting polymer (PSP) for NIR‐II… read more here.
Keywords: self sacrificially; nir fluorescence; photodynamic immunotherapy; psp ... See more keywords
Cell‐Specific Dysregulation of Iron and Oxygen Homeostasis as a Novel Pathophysiology in PSP
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26540
Abstract: Progressive supranuclear palsy (PSP) is a 4R‐tauopathy showing heterogeneous tau cytopathology commencing in the globus pallidus (GP) and the substantia nigra (SN), regions also associated with age‐related iron accumulation. Abnormal iron levels have been extensively… read more here.
Keywords: cell; psp; iron; pathology ... See more keywords
Correlation between Sternal Slope Angle and Primary Spontaneous Pneumothorax in Young Males, a Propensity Score Match Analysis
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Anatomy"
DOI: 10.1002/ca.23461
Abstract: It is generally accepted that primary spontaneous pneumothorax (PSP) is found mostly in tall, thin young males. However, the precise etiology of PSP is unclear. We compared some thoracic structural angles of PSPs and controls… read more here.
Keywords: slope; psp; sternal slope; young males ... See more keywords
Reply to: “MRI Linear Measurements in Normal Pressure Hydrocephalus Versus Progressive Supranuclear Palsy”
Sign Up to like & getrecommendations! Published in 2020 at "Movement Disorders"
DOI: 10.1002/mds.28337
Abstract: We thank Ugga and colleagues for their interest and positive comments on our recent article. We agree that differentiating between idiopathic normal pressure hydrocephalus (iNPH) and progressive supranuclear palsy (PSP) is often challenging and that… read more here.
Keywords: supranuclear palsy; article; psp; normal pressure ... See more keywords
Application of the mPSPRS to the Salerno Cohort and a Comparison Between PSP‐RS and vPSP
Sign Up to like & getrecommendations! Published in 2021 at "Movement Disorders"
DOI: 10.1002/mds.28757
Abstract: We read with interest the article from Grötsch et al on the modified version of the Progressive Supranuclear Palsy Rating Scale (mPSPRS). Here, we applied the mPSPRS to our singlecenter PSP cohort and investigated its… read more here.
Keywords: mpsprs; psp; change; psp vpsp ... See more keywords
Glioblastoma radiomics: can genomic and molecular characteristics correlate with imaging response patterns?
Sign Up to like & getrecommendations! Published in 2018 at "Neuroradiology"
DOI: 10.1007/s00234-018-2060-y
Abstract: PurposeFor glioblastoma (GBM), imaging response (IR) or pseudoprogression (PSP) is frequently observed after chemoradiation and may connote a favorable prognosis. With tumors categorized by the Cancer Genome Atlas Project (mesenchymal, classical, neural, and proneural) and… read more here.
Keywords: imaging response; psp; radiomics genomic; glioblastoma radiomics ... See more keywords
Validation of the new pathology staging system for progressive supranuclear palsy
Sign Up to like & getrecommendations! Published in 2021 at "Acta Neuropathologica"
DOI: 10.1007/s00401-021-02298-z
Abstract: Progressive supranuclear palsy (PSP) is a neurodegenerative disorder associated with neuroglial accumulation of 4-repeat tau protein [2]. Kovacs et al. [1] have recently proposed a new semi-quantitative six-stage system to categorise the severity of PSP… read more here.
Keywords: tau; system; staging system; psp ... See more keywords
[18F]AV-1451 binding to neuromelanin in the substantia nigra in PD and PSP
Sign Up to like & getrecommendations! Published in 2017 at "Brain Structure and Function"
DOI: 10.1007/s00429-017-1507-y
Abstract: This study investigated binding of [18F]AV-1451 to neuromelanin in the substantia nigra of patients with Parkinson’s disease (PD) and progressive supranuclear palsy (PSP). [18F]AV-1451 is a positron emission tomography radiotracer designed to bind pathological tau.… read more here.
Keywords: psp; neuromelanin substantia; binding; substantia nigra ... See more keywords
Dysphagia in Progressive Supranuclear Palsy
Sign Up to like & getrecommendations! Published in 2019 at "Dysphagia"
DOI: 10.1007/s00455-019-10073-2
Abstract: Progressive supranuclear palsy (PSP) is the most common Parkinson-Plus syndrome and is associated with early onset of dysphagia relative to Parkinson Disease. The current study contributes to the growing understanding of swallowing dysfunction in PSP… read more here.
Keywords: supranuclear palsy; psp; dysphagia; progressive supranuclear ... See more keywords
A novel dual-covering method in video-assisted thoracic surgery for pediatric primary spontaneous pneumothorax
Sign Up to like & getrecommendations! Published in 2019 at "Surgery Today"
DOI: 10.1007/s00595-019-01785-x
Abstract: BackgroundPrimary spontaneous pneumothorax (PSP) generally occurs in young adults, whereas pediatric PSP is uncommon. It is difficult to source reliable data on pediatric PSP, the management of which is based on guidelines for adult PSP;… read more here.
Keywords: surgery; recurrence; spontaneous pneumothorax; psp ... See more keywords