Altered levels of circulating CD8+CXCR5+PD-1+T follicular cytotoxic cells in primary Sjögren’s syndrome
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DOI: 10.1007/s10067-022-06098-y
Abstract: Circulating CD8+ T-cells expressing the C-X-C chemokine receptor type 5 (CXCR5) (CD8+CXCR5+T), a recently identified follicular cytotoxic T cell subset, are involved in antiviral immunity and autoimmunity, but their abundance and role in the pathogenesis… read more here.
Keywords: cd8 treg; cd8 cxcr5; cd8; pss patients ... See more keywords
Expression of BAFF and BAFF receptors in primary Sjögren’s syndrome patients with ectopic germinal center-like structures
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DOI: 10.1007/s10238-020-00637-0
Abstract: B cell-activating factor (BAFF) is an essential cytokine in primary Sjögren’s syndrome (pSS) physiopathology. It has been reported that pSS patients develop germinal center-like (GC-like) structures in their minor salivary glands (MSGs). BAFF, BAFF-R, TACI,… read more here.
Keywords: gren syndrome; baff baff; like structures; baff ... See more keywords
LncRNA and mRNA expression profile of peripheral blood mononuclear cells in primary Sjögren’s syndrome patients
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DOI: 10.1038/s41598-020-76701-2
Abstract: The aim of this study was to elucidate the expression profile and the potential role of long non-coding RNA (LncRNA) in the peripheral blood mononuclear cells of primary Sjögren’s syndrome (pSS) patients. RNA-seq technology was… read more here.
Keywords: blood mononuclear; expression profile; peripheral blood; expression ... See more keywords
Pulmonary involvement in primary Sjögren’s syndrome, as measured by the ESSDAI
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DOI: 10.1080/03009742.2019.1634221
Abstract: Objective: Systemic features influence disease prognosis and choice of treatment in primary Sjögren’s syndrome (pSS). Our aim was to investigate the prevalence of pulmonary involvement in pSS patients and to classify patients according to the… read more here.
Keywords: pulmonary involvement; rheumatology; pss patients; gren syndrome ... See more keywords
Follicular helper and follicular cytotoxic T cells in primary Sjögren’s Syndrome: clues for an abnormal antiviral response as a pathogenic mechanism
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DOI: 10.1080/07853890.2018.1561890
Abstract: Introduction: In chronic viral infections, T follicular helper (Tfh) cells are crucial to sustain CD8 cytotoxic T cells in face of the persistence of viral antigens. Moreover, the usual Th1 profile that is associated with… read more here.
Keywords: cytotoxic cells; pss; disease; pss patients ... See more keywords
Elevated level of circulating CD4+Helios+FoxP3+ cells in primary Sjogren’s syndrome patients
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DOI: 10.1080/14397595.2016.1226470
Abstract: Abstract Objective: This study was designed to investigate the expression of regulatory T cells in primary Sjögren’s Syndrome (pSS) and to evaluate the clinical role of CD4 + Helios+ FoxP3+ cells in pSS patients. Methods: CD4 + FoxP3+ T cells in… read more here.
Keywords: elevated level; helios foxp3; pss patients; foxp3 cells ... See more keywords
FDG-PET/CT discriminates between patients with and without lymphomas in primary Sjögren's syndrome.
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DOI: 10.1093/rheumatology/kead071
Abstract: OBJECTIVES To assess the usefulness of FDG-PET/CT 1) to discriminate between pSS patients with and without lymphomas and 2) to evaluate systemic disease activity in pSS. METHODS ACR-EULAR-positive pSS patients who underwent FDG-PET/CT were included.… read more here.
Keywords: lymphoma; without lymphomas; pss patients; fdg pet ... See more keywords
Decreased circulating CXCR3 + CCR9+T helper cells are associated with elevated levels of their ligands CXCL10 and CCL25 in the salivary gland of patients with Sjögren’s syndrome to facilitate their concerted migration
Sign Up to like & getrecommendations! Published in 2019 at "Scandinavian Journal of Immunology"
DOI: 10.1111/sji.12852
Abstract: CCR9 + T helper (Th) cells can induce Sjögren‐like symptoms in mice and both CCR9 + Th cells and their ligand CCL25 are increased in the salivary glands of primary Sjögren's syndrome (pSS) patients. Increased… read more here.
Keywords: cxcr3; ccr9 cells; salivary gland; ccr9 ... See more keywords
SAT0461 Ultrasonography of salivary glands in primary sjogren’s syndrome and association with disease activity, serological markers and biopsy of minor salivary glands
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.5165
Abstract: Background Parenchimal inhomogeneity of the salivary glands (SG) is the most relevant ultrasonografic (US) feature for diagnosis primary Sjogren’s syndrome (pSS). Objectives To analysis parechymal echostructure of SG in patients with established pSS and association… read more here.
Keywords: disease activity; disease; salivary glands; pss patients ... See more keywords
THU0346 Determinants of sonographic glandular damage in a large cohort of patients with primary sjÖgren’s syndrome and its impact on salivary gland dysfunction
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.5843
Abstract: Background Salivary gland ultrasonography (SGUS) has increasingly appeared as a valid tool to characterise major salivary glands involvement in primary Sjögren’s syndrome (pSS). An international score based on the number and location of the hypoechoic… read more here.
Keywords: cohort; salivary gland; damage; gland ... See more keywords
FRI0652 SERUM CXCL13 LEVELS ARE ASSOCIATED WITH LYMPHOMA RISK AND LYMPHOMA OCCURRENCE IN PRIMARY SJöGREN’S SYNDROME
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DOI: 10.1136/annrheumdis-2019-eular.4134
Abstract: Background Primary Sjögren’s syndrome (pSS) is an autoimmune disease characterized by an increased risk for non-Hodgkin lymphoma (NHL) development. Ectopic germinal center (GC) formation in the salivary gland (SG) epithelium of pSS patients is thought… read more here.
Keywords: lymphoma; risk; cxcl13 levels; cxcl13 ... See more keywords