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   Articles with "pstat3" as a keyword



Invasive growth of brain metastases is linked to CHI3L1 release from pSTAT3-positive astrocytes.

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recommendations! Published in 2024 at "Neuro-oncology"

DOI: 10.1093/neuonc/noae013

Abstract: BACKGROUND Compared to minimally invasive brain metastases (MI BrM), highly invasive (HI) lesions form abundant contacts with cells in the peritumoral brain parenchyma and are associated with poor prognosis. Reactive astrocytes (RAs) labeled by phosphorylated… read more here.

Keywords: brain; culture; pstat3; brm ... See more keywords

TMIC-08. PATTERNS OF PSTAT3 EXPRESSION IN REACTIVE ASTROCYTES OF BRAIN METASTASES FROM NON-SMALL CELL LUNG CANCER AND CORRELATIONS WITH OUTCOME

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recommendations! Published in 2024 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noae165.1186

Abstract: pSTAT3 expression in peritumoral reactive astrocytes (RA) of brain metastases (BM) from breast cancer may favor a pro-metastatic environment and negatively affect the intracranial progression-free survival (i-PFS) (Pellerino, 2023). We aim to evaluate whether pSTAT3… read more here.

Keywords: astrocytes brain; brain metastases; pstat3; reactive astrocytes ... See more keywords

P11.06.A PATTERNS OF PSTAT3 EXPRESSION IN REACTIVE ASTROCYTES OF BRAIN METASTASES FROM NON-SMALL CELL LUNG CANCER AND CORRELATIONS WITH OUTCOME

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recommendations! Published in 2025 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaf193.345

Abstract: pSTAT3 expression in peritumoral reactive astrocytes (RA) of brain metastases (BrM) from breast cancer may favor a pro-metastatic environment and negatively affect the intracranial progression-free survival (i-PFS) (Pellerino, Neurooncol Adv. 2023). We aim to evaluate… read more here.

Keywords: astrocytes brain; pstat3; reactive astrocytes; brm ... See more keywords

TMIC-07. pSTAT3 expression in patients with brain metastases from breast cancer: association with molecular subtypes and impact on overall survival

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recommendations! Published in 2025 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaf201.1762

Abstract: A high pSTAT3 expression in reactive astrocytes (RA) of brain metastases (BrM) promotes tumor growth in preclinical models (Priego, 2018) and negatively affects the intracranial progression-free survival in BrM from breast cancer (BC) (Pellerino, 2023).… read more here.

Keywords: high pstat3; brain metastases; pstat3; brm ... See more keywords

Prognostic significance of pSTAT3 expression in feline mammary carcinomas

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recommendations! Published in 2025 at "Veterinary Pathology"

DOI: 10.1177/03009858251338851

Abstract: Feline mammary carcinomas (FMCs) have a highly malignant and metastatic behavior and are associated with a poor prognosis. There is a need to identify new effective therapies for FMC. Signal transducer and activator of transcription… read more here.

Keywords: mammary carcinomas; pstat3; feline mammary; index ... See more keywords

Expression of the activation markers Blimp1, Foxp1 and pStat3 in extranodal diffuse large B-cell lymphomas.

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recommendations! Published in 2017 at "Histology and histopathology"

DOI: 10.14670/hh-11-852

Abstract: Different studies have suggested that the expression of biomarkers related to lymphoid cell activation may provide information on the behavior of DLBCL. Most studies have concentrated on nodal or a mixture of nodal and extranodal… read more here.

Keywords: pstat3; activation markers; expression; markers blimp1 ... See more keywords

Mouse Microglial Calcitonin Receptor Knockout Impairs Hypothalamic Amylin Neuronal pSTAT3 Signaling but Lacks Major Metabolic Consequences

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recommendations! Published in 2022 at "Metabolites"

DOI: 10.3390/metabo12010051

Abstract: Amylin and leptin synergistically interact in the arcuate nucleus of the hypothalamus (ARC) to control energy homeostasis. Our previous rodent studies suggested that amylin-induced interleukin-6 release from hypothalamic microglia may modulate leptin signaling in agouti-related… read more here.

Keywords: pstat3; microglial calcitonin; calcitonin receptor; mice ... See more keywords