PSTPIP2 attenuates joint damage and suppresses inflammation in adjuvant-induced arthritis.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.172558
Abstract: Proline-serine-threonine-phosphatase-interacting protein 2 (PSTPIP2) is related to inflammation. In this study, we investigated the function of PSTPIP2 in adjuvant-induced arthritis (AIA) by using adeno-associated virus (AAV) to overexpress PSTPIP2 in rat. AIA rats were developed… read more here.
Keywords: induced arthritis; pstpip2; inflammation; adjuvant induced ... See more keywords
PSTPIP2 Inhibits the Inflammatory Response and Proliferation of Fibroblast-Like Synoviocytes in vitro
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DOI: 10.3389/fphar.2018.01432
Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease and its pathogenesis remains unclear. Fibroblast-like synoviocytes (FLSs) play an important role in the pathogenesis of RA. Proline-serine-threonine phosphatase interacting protein 2 (PSTPIP2) is an adaptor… read more here.
Keywords: fibroblast like; response; like synoviocytes; inflammatory response ... See more keywords
PSTPIP2 ameliorates aristolochic acid nephropathy by suppressing interleukin-19-mediated neutrophil extracellular trap formation
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DOI: 10.7554/elife.89740
Abstract: Aristolochic acid nephropathy (AAN) is a progressive kidney disease caused by herbal medicines. Proline–serine–threonine phosphatase-interacting protein 2 (PSTPIP2) and neutrophil extracellular traps (NETs) play important roles in kidney injury and immune defense, respectively, but the… read more here.
Keywords: aristolochic acid; acid nephropathy; pstpip2; formation ... See more keywords