Better Approaches to Derisking Psychiatric Drug Development are Needed, Not New Funding Mechanisms
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Psychopharmacology"
DOI: 10.1097/jcp.0000000000001609
Abstract: Abstract Background The pulling back of large pharma from psychiatric drug development over the last 15 years has been a cause of concern. The uncertainty of success with any novel mechanism raises questions concerning whether… read more here.
Keywords: funding mechanisms; development; drug development; psychiatric drug ... See more keywords
The doors of precision: Reenergizing psychiatric drug development with psychedelics and open access computational tools.
Sign Up to like & getrecommendations! Published in 2022 at "Science advances"
DOI: 10.1126/sciadv.abp8283
Abstract: Psychedelics paired with new applications of computational tools might help bypass the imprecision of psychiatric diagnosis and connect measures of behavior to specific physiologic targets. read more here.
Keywords: psychiatric drug; reenergizing psychiatric; precision reenergizing; computational tools ... See more keywords
Ketamine—From an Anesthetic to a Psychiatric Drug: Mechanisms of Action, Clinical Applications and Potential Risks
Sign Up to like & getrecommendations! Published in 2025 at "Molecules"
DOI: 10.3390/molecules30132824
Abstract: Ketamine, originally developed as an anesthetic, is gaining increasing attention due to its multifaceted pharmacological properties. In addition to its use in anesthesia, ketamine exerts potent analgesic effects via N-methyl-D-aspartate (NMDA) receptor antagonism, modulating pain… read more here.
Keywords: drug mechanisms; mechanisms action; psychiatric drug; action clinical ... See more keywords