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   Articles with "psychiatric neurodevelopmental" as a keyword



Pleiotropic contribution of rbfox1 to psychiatric and neurodevelopmental phenotypes in two zebrafish models

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recommendations! Published in 2024 at "Translational Psychiatry"

DOI: 10.1038/s41398-024-02801-6

Abstract: RBFOX1 is a highly pleiotropic gene that contributes to several psychiatric and neurodevelopmental disorders. Both rare and common variants in RBFOX1 have been associated with several psychiatric conditions, but the mechanisms underlying the pleiotropic effects… read more here.

Keywords: psychiatric neurodevelopmental; rbfox1; contribution rbfox1; pleiotropic contribution ... See more keywords

Genetics of monozygotic twins reveals the impact of environmental sensitivity on psychiatric and neurodevelopmental phenotypes

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recommendations! Published in 2025 at "Nature Human Behaviour"

DOI: 10.1038/s41562-025-02193-7

Abstract: Individual sensitivity to environmental exposures may be genetically influenced. This genotype-by-environment interplay implies differences in phenotypic variance across genotypes, but these variants have proven challenging to detect. Genome-wide association studies of monozygotic twin differences are… read more here.

Keywords: genetics; psychiatric neurodevelopmental; monozygotic twins; sensitivity ... See more keywords

Exploration of large, rare copy number variants associated with psychiatric and neurodevelopmental disorders in individuals with anorexia nervosa

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recommendations! Published in 2017 at "Psychiatric Genetics"

DOI: 10.1097/ypg.0000000000000172

Abstract: Anorexia nervosa (AN) is a serious and heritable psychiatric disorder. To date, studies of copy number variants (CNVs) have been limited and inconclusive because of small sample sizes. We conducted a case-only genome-wide CNV survey… read more here.

Keywords: psychiatric neurodevelopmental; copy number; anorexia nervosa; cnvs ... See more keywords

Neural correlates of N‐back task performance and proposal for corresponding neuromodulation targets in psychiatric and neurodevelopmental disorders

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recommendations! Published in 2022 at "Psychiatry and Clinical Neurosciences"

DOI: 10.1111/pcn.13442

Abstract: Working memory (WM) deficit represents the most common cognitive impairment in psychiatric and neurodevelopmental disorders, making the identification of its neural substrates a crucial step towards the conceptualization of restorative interventions. We present a meta‐analysis… read more here.

Keywords: neural correlates; neurodevelopmental disorders; back task; task performance ... See more keywords

Exploring glucagon-like peptide-1 receptor agonists as potential disease-modifying agent in psychiatric and neurodevelopmental conditions: evidence from a drug target Mendelian randomization

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recommendations! Published in 2025 at "BMC Psychiatry"

DOI: 10.1186/s12888-025-06914-0

Abstract: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have recently received Food and Drug Administration (FDA) approval for obesity management. However, the causal relationship between GLP-1RAs and psychiatric and neurodevelopmental conditions remains unclear. We used Mendelian randomization (MR)… read more here.

Keywords: neurodevelopmental conditions; psychiatric neurodevelopmental; disorder; risk ... See more keywords