Association of Primary Care Consultation Patterns With Early Signs and Symptoms of Psychosis
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2018.5174
Abstract: Key Points Question Are primary care consultation patterns for prespecified nonspecific symptoms associated with a psychotic diagnosis? Findings In this case-control study of 11 690 adults with psychosis and 81 793 matched controls without psychosis, 12 clinical… read more here.
Keywords: consultation patterns; primary care; care consultation; psychosis ... See more keywords
Longitudinal Cognitive Changes in Young Individuals at Ultrahigh Risk for Psychosis
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Psychiatry"
DOI: 10.1001/jamapsychiatry.2018.1668
Abstract: Importance Cognitive deficits are a key feature of risk for psychosis. Longitudinal changes in cognitive architecture may be associated with the social and occupational functioning in young people. Objectives To examine longitudinal profiles of cognition… read more here.
Keywords: risk; ultrahigh risk; risk psychosis; psychosis ... See more keywords
Risk of Psychosis Among Refugees: A Systematic Review and Meta-analysis.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2019.1937
Abstract: Importance This systematic review and meta-analysis is, to date, the first and most comprehensive to focus on the incidence of non-affective psychoses among refugees. Objective To assess the relative risk (RR) of incidence of non-affective… read more here.
Keywords: risk; refugees compared; non affective; nonrefugee migrants ... See more keywords
Prevention of Psychosis: Advances in Detection, Prognosis, and Intervention.
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DOI: 10.1001/jamapsychiatry.2019.4779
Abstract: Importance Detection, prognosis, and indicated interventions in individuals at clinical high risk for psychosis (CHR-P) are key components of preventive psychiatry. Objective To provide a comprehensive, evidence-based systematic appraisal of the advancements and limitations of… read more here.
Keywords: prognosis; chr individuals; detection prognosis; psychosis ... See more keywords
An Investigation of Psychosis Subgroups With Prognostic Validation and Exploration of Genetic Underpinnings: The PsyCourse Study.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2019.4910
Abstract: Importance Identifying psychosis subgroups could improve clinical and research precision. Research has focused on symptom subgroups, but there is a need to consider a broader clinical spectrum, disentangle illness trajectories, and investigate genetic associations. Objective… read more here.
Keywords: illness courses; psychosis subgroups; validation; disorder ... See more keywords
Association Between Early Contact With Mental Health Services After an Offense and Reoffending in Individuals Diagnosed With Psychosis.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2020.1255
Abstract: Importance Psychosis is a known risk factor for offending behavior, but little is known about the association between clinical contact with mental health services after an offense and reoffending. Objective To examine the association between… read more here.
Keywords: health; health services; contact; contact mental ... See more keywords
Prediction Tool for Individual Outcome Trajectories Across the Next Year in First-Episode Psychosis in Coordinated Specialty Care.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2022.3571
Abstract: Importance In coordinated specialty care (CSC) settings for people with a first episode of psychosis, the development of reliable, validated individual-level prediction tools for key outcomes may be informative for shared clinician and client decision-making.… read more here.
Keywords: tool; level; prediction; work ... See more keywords
Effect of Technology-Enhanced Screening in Addition to Standard Targeted Clinician Education on the Duration of Untreated Psychosis: A Cluster Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2022.4436
Abstract: Importance Reducing the duration of untreated psychosis (DUP) is essential to improving outcomes for people with first-episode psychosis (FEP). Current US approaches are insufficient to reduce DUP to international standards of less than 90 days.… read more here.
Keywords: trial; group; clinician education; active screening ... See more keywords
Dorsal striatial hypoconnectivity predicts antipsychotic medication treatment response in first‐episode psychosis and unmedicated patients with schizophrenia
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2625
Abstract: The dorsal striatum, comprised of the caudate and putamen, is implicated in the pathophysiology of psychosis spectrum disorders. Given the high concentration of dopamine receptors in the striatum, striatal dopamine imbalance is a likely cause… read more here.
Keywords: caudate putamen; psychosis; treatment; treatment response ... See more keywords
Upper cerebellar glucose hypermetabolism in patients with temporal lobe epilepsy and interictal psychosis
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DOI: 10.1002/epi4.12645
Abstract: Psychosis is an important comorbidity in epilepsy, but its pathophysiology is still unknown. The imaging modality 18F‐fluorodeoxyglucose‐positron emission tomography (18F‐FDG PET) is widely used to measure brain glucose metabolism, and we speculated that 18F‐FDG PET… read more here.
Keywords: lobe epilepsy; temporal lobe; upper cerebellar; epilepsy ... See more keywords
Distinct and opposite profiles of connectivity during self‐reference task and rest in youth at clinical high risk for psychosis
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DOI: 10.1002/hbm.24595
Abstract: Self‐reference is impaired in psychotic disorders such as schizophrenia, associated with disability, and closely related to characteristic patterns of aberrant brain connectivity. However, at present, it is unclear whether self‐reference is impacted in pathogenesis of… read more here.
Keywords: self reference; task; connectivity; reference task ... See more keywords