Modafinil and its structural analogs as atypical dopamine uptake inhibitors and potential medications for psychostimulant use disorder.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in pharmacology"
DOI: 10.1016/j.coph.2020.07.007
Abstract: Pharmacotherapeutics for treatment of psychostimulant use disorder are still an unmet medical goal. Recently, off label use of modafinil (MOD), an approved medication for treatment of sleep disturbances, has been tested as a therapeutic for… read more here.
Keywords: structural analogs; use; psychostimulant use; modafinil structural ... See more keywords
New Drugs, Old Targets: Tweaking the Dopamine System to Treat Psychostimulant Use Disorders.
Sign Up to like & getrecommendations! Published in 2021 at "Annual review of pharmacology and toxicology"
DOI: 10.1146/annurev-pharmtox-030220-124205
Abstract: The abuse of illicit psychostimulants such as cocaine and methamphetamine continues to pose significant health and societal challenges. Despite considerable efforts to develop medications to treat psychostimulant use disorders, none have proven effective, leaving an… read more here.
Keywords: treat psychostimulant; psychostimulant use; dopamine; new drugs ... See more keywords
Psychostimulant Use Disorder, an Unmet Therapeutic Goal: Can Modafinil Narrow the Gap?
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2021.656475
Abstract: The number of individuals affected by psychostimulant use disorder (PSUD) has increased rapidly over the last few decades resulting in economic, emotional, and physical burdens on our society. Further compounding this issue is the current… read more here.
Keywords: unmet therapeutic; use; psychostimulant use; disorder unmet ... See more keywords
An Overview of Adolescent Psychostimulant Use.
Sign Up to like & getrecommendations! Published in 2023 at "Pediatric annals"
DOI: 10.3928/19382359-20230307-05
Abstract: Adolescence marks a period of significant neural maturation and development of lifelong habits, including the potential use of recreational psychostimulant drugs. Increased prevalence of drug adulteration and fatalities related to drug overdose pose new challenges… read more here.
Keywords: psychostimulant use; adolescent psychostimulant; psychostimulant; overview adolescent ... See more keywords