The new guideline for evaluating effects of psychotropic drugs on the performance to drive a motor vehicle in Japan: Comparison with US FDA guideline.
Sign Up to like & getrecommendations! Published in 2023 at "Neuropsychopharmacology reports"
DOI: 10.1002/npr2.12339
Abstract: In December 2022, the new guideline for evaluating the effect of psychotropic drugs on the performance to drive a motor vehicle was issued by the Ministry of Health, Labour and Welfare (MHLW) and implemented in… read more here.
Keywords: guideline evaluating; guideline; new guideline; drugs performance ... See more keywords
Differential effects of psychotropic drugs on microbiome composition and gastrointestinal function
Sign Up to like & getrecommendations! Published in 2018 at "Psychopharmacology"
DOI: 10.1007/s00213-018-5006-5
Abstract: RationaleGrowing evidence supports a role for the microbiota in regulating gut-brain interactions and, thus, psychiatric disorders. Despite substantial scientific efforts to delineate the mechanism of action of psychotropic medications at a central nervous system (CNS)… read more here.
Keywords: drugs microbiome; gut; differential effects; effects psychotropic ... See more keywords
Application of the STOPP criteria in hospitalised elderly patients to detect and optimise inappropriate psychopharmaceutical prescriptions
Sign Up to like & getrecommendations! Published in 2018 at "European Geriatric Medicine"
DOI: 10.1007/s41999-018-0091-x
Abstract: BackgroundPsychotropic drugs are frequently used in the elderly population, but their inappropriate prescription can cause numerous adverse effects and interactions.ObjectiveTo evaluate the impact of a multidisciplinary intervention to detect and optimise inappropriate prescriptions of psychotropic… read more here.
Keywords: intervention; detect optimise; optimise inappropriate; stopp criteria ... See more keywords
[Pharmacoresistance to psychotropic drugs in children and adolescents: Pharmacogenetic anomalies of cytochrome P450 2D6].
Sign Up to like & getrecommendations! Published in 2021 at "L'Encephale"
DOI: 10.1016/j.encep.2020.09.010
Abstract: OBJECTIVES Some patients in child and adolescent psychiatry present resistance to psychotropic drugs, often resulting in polytherapy, an increased risk of adverse events, and more frequent and longer hospitalisation. Psychotropic drugs are mainly metabolised in… read more here.
Keywords: phenotype; psychotropic; children adolescents; cytochrome p450 ... See more keywords
Driving Ability and Psychotropic Drugs: Introduction, Epidemiology and General Aspects
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DOI: 10.1016/j.eurpsy.2017.01.212
Abstract: Psychiatric illness, psychotropic drugs and driving ability. For most people driving is an important activity in daily life affecting physical, social, and economic well-being. Driving mobility is also an important part of one's self-identity that… read more here.
Keywords: risk; driving ability; road; epidemiology ... See more keywords
Stability of ten psychotropic drugs in formalin-fixed porcine liver homogenates.
Sign Up to like & getrecommendations! Published in 2019 at "Forensic science international"
DOI: 10.1016/j.forsciint.2019.110136
Abstract: In forensic toxicology studies, drug concentrations must be estimated by the analytical data of formalin-fixed tissues if fresh or frozen tissue specimens are not available. We wished to investigate the stability and time-course of metabolism/degradation… read more here.
Keywords: liver homogenates; formalin fixed; ten psychotropic; porcine liver ... See more keywords
Association of variants in SH2B1 and RABEP1 with worsening of low-density lipoprotein and glucose parameters in patients treated with psychotropic drugs.
Sign Up to like & getrecommendations! Published in 2017 at "Gene"
DOI: 10.1016/j.gene.2017.07.005
Abstract: Genetic factors associated with Body Mass Index (BMI) have been widely studied over the last decade. We examined whether genetic variants previously associated with BMI in the general population are associated with cardiometabolic parameter worsening… read more here.
Keywords: sh2b1 rabep1; variants sh2b1; rabep1 worsening; association variants ... See more keywords
Predicting Hepatic Clearance of Psychotropic Drugs in Isolated Perfused Fish Livers Using a Combination of Two In Vitro Assays.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental science & technology"
DOI: 10.1021/acs.est.2c03017
Abstract: In vitro biotransformation assays with primary trout hepatocytes (RT-HEP) or liver subcellular fractions (RT-S9) have been proposed as valuable tools to help scientists and regulators better understand the toxicokinetics of chemicals. While both assays have… read more here.
Keywords: active transport; combination; isolated perfused; hepatic clearance ... See more keywords
Psychotropic Drugs and Outcome in Patients Receiving Anticoagulant Therapy for Venous Thromboembolism.
Sign Up to like & getrecommendations! Published in 2020 at "Thrombosis and haemostasis"
DOI: 10.1055/s-0040-1708482
Abstract: BACKGROUND The influence (if any) of the use of psychotropic drugs on outcome in patients receiving anticoagulant therapy for venous thromboembolism (VTE) has not been consistently evaluated. METHODS We used data from the RIETE (Registro… read more here.
Keywords: risk; anticoagulant therapy; outcome patients; drugs outcome ... See more keywords
Quantification of 15 Psychotropic Drugs in Serum and Postmortem Blood Samples after a Modified Mini-QuEChERS by UHPLC-MS-MS.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of analytical toxicology"
DOI: 10.1093/jat/bky006
Abstract: The aim of the study was to develop a LC-MS-MS method able to detect and quantify a number of frequently prescribed antipsychotic and antidepressant drugs for toxicological purposes. Separation of compounds was performed on a… read more here.
Keywords: drugs serum; blood samples; serum postmortem; quantification psychotropic ... See more keywords
Electrocardiogram Characteristics and Their Association With Psychotropic Drugs Among Patients With Schizophrenia.
Sign Up to like & getrecommendations! Published in 2019 at "Schizophrenia bulletin"
DOI: 10.1093/schbul/sbz064
Abstract: BACKGROUND There are limited data on electrocardiogram (ECG) characteristics and their association with psychotropic drugs in schizophrenia. METHODS Using a cross-sectional design, we included Danish primary care patients with first-time digital ECGs from 2001 to… read more here.
Keywords: patients schizophrenia; among patients; association psychotropic; characteristics association ... See more keywords