Upregulation of miR-196b-5p attenuates BCG uptake via targeting SOCS3 and activating STAT3 in macrophages from patients with long-term cigarette smoking-related active pulmonary tuberculosis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-018-1654-9
Abstract: BackgroundCigarette smoking (CS) triggers an intense and harmful inflammatory response in lungs mediated by alveolar and blood macrophages, monocytes, and neutrophils and is closely associated with prevalence of tuberculosis (TB). The risk of death in… read more here.
Keywords: long term; patients long; tuberculosis; mir 196b ... See more keywords
The Incidence and Risk Factors of Hyponatremia in Pulmonary Tuberculosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Endocrine Society"
DOI: 10.1210/jendso/bvac130
Abstract: Abstract Context The syndrome of inappropriate antidiuresis (SIAD) with euvolemic hyponatremia may occur in patients with pulmonary tuberculosis (PTB), but little is known about the clinical characteristics of SIAD-associated hyponatremia in PTB patients. Objective This… read more here.
Keywords: hyponatremia; pulmonary tuberculosis; risk factors; ptb patients ... See more keywords
Association between depression and malnutrition in pulmonary tuberculosis patients: A cross-sectional study
Sign Up to like & getrecommendations! Published in 2022 at "World Journal of Clinical Cases"
DOI: 10.12998/wjcc.v10.i14.4395
Abstract: BACKGROUND Depression has been reported to be prevalent in patients with pulmonary tuberculosis (PTB). Moreover, several clinical symptoms of PTB and depression overlap, such as loss of appetite and malnutrition. However, the association between depression… read more here.
Keywords: association depression; depression; depression malnutrition; malnutrition ... See more keywords
Association of Three SNPs Loci of Kelch-Like-ECH-Associated Protein 1 (Human) with Tuberculosis in Chinese Han Population
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of General Medicine"
DOI: 10.2147/ijgm.s373555
Abstract: Purpose Progression from latent tuberculosis infection (LTBI) to pulmonary TB (PTB) was associated with genetic polymorphisms, but there were limited genetic polymorphism data on LTBI and PTB. We aimed at examining the association of KEAP1… read more here.
Keywords: tuberculosis; ptb; snps; ptb patients ... See more keywords
Impact of m6A demethylase (ALKBH5, FTO) genetic polymorphism and expression levels on the development of pulmonary tuberculosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.1074380
Abstract: Objective The m6A methylation was involved in the pathogenesis of pulmonary tuberculosis (PTB), and our study aimed to reveal the potential association of m6A demethylase (ALKBH5, FTO) genes variation, expression levels and PTB. Methods Eight… read more here.
Keywords: alkbh5 fto; m6a demethylase; ptb patients; expression levels ... See more keywords
Clinical relevance of vitamin B12 level and vitamin B12 metabolic gene variation in pulmonary tuberculosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.947897
Abstract: The aim of this study was to assess the association of vitamin B12 level and single nucleotide polymorphisms (SNPs) in vitamin B12 metabolic genes with pulmonary tuberculosis (PTB) in Chinese Han population. The plasma vitamin… read more here.
Keywords: vitamin; vitamin b12; ptb patients; b12 level ... See more keywords
Exploring the association between Th17 pathway gene polymorphisms and pulmonary tuberculosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.994247
Abstract: Th17 cells play a key role in immunity against Mycobacterium tuberculosis (MTB), and this study aimed to explore the association of Th17 pathway gene polymorphisms with pulmonary tuberculosis (PTB) susceptibility in a Chinese population. A… read more here.
Keywords: tuberculosis; gene; ptb patients; th17 pathway ... See more keywords
PD-L1 Expression in Monocytes Correlates with Bacterial Burden and Treatment Outcomes in Active Pulmonary Tuberculosis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031619
Abstract: The PD-1/PD-L1 pathway is critical in T cell biology; however, the role of the PD-1/PD-L1 pathway in clinical characteristics and treatment outcomes in pulmonary tuberculosis (PTB) patients is unclear. We prospectively enrolled PTB, latent TB… read more here.
Keywords: expression monocytes; tuberculosis; expression; treatment outcomes ... See more keywords