Partial Truncation of the C-Terminal Domain of PTCH1 in Cancer Enhances Autophagy and Metabolic Adaptability
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DOI: 10.3390/cancers15020369
Abstract: Simple Summary We have recently reported that the cytosolic C-terminal domain (CTD) of the tumour suppressor PTCH1, the Hedgehog proteins receptor, interacts with the autophagy-related protein ATG101 and impairs autophagic flux. In this study, we… read more here.
Keywords: interaction; terminal domain; autophagic flux; ptch1 cancer ... See more keywords