DNMT3A Mutations Identify a Prognostic Subgroup in Peripheral T-Cell Lymphoma
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DOI: 10.1182/blood-2020-143335
Abstract: Background Mutational profiling of angioimmunoblastic T-cell lymphoma (AITL) and peripheral T-cell lymphoma not otherwise specified (PTCL-NOS) has revealed recurrent mutations in DNMT3A, a de novo methyltransferase. DNMT3A catalyzes the conversion of cytosine to 5-methylcytosine (5-mC)… read more here.
Keywords: ptcl tbx21; cell lymphoma; dnmt3a; cell ... See more keywords