Exploring PTDH–P450BM3 Variants for the Synthesis of Drug Metabolites
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DOI: 10.1002/cbic.201700470
Abstract: The conversion of a series of pharmaceutical compounds was examined with three variants of cytochrome P450BM3 fused to phosphite dehydrogenase (PTDH) to enable cofactor recycling. Conditions for enzyme production were optimized, and the purified PTDH–P450BM3… read more here.
Keywords: p450bm3; ptdh p450bm3; p450bm3 variants; variants synthesis ... See more keywords