A PtdIns(3,4,5)P3 dispersal switch engages cell ratcheting at specific cell surfaces.
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DOI: 10.1016/j.devcel.2021.08.016
Abstract: Force generation in epithelial tissues is often pulsatile, with actomyosin networks generating contractile forces before cyclically disassembling. This pulsed nature of cytoskeletal forces implies that there must be ratcheting mechanisms that drive processive transformations in… read more here.
Keywords: ptdins dispersal; cell surfaces; dispersal switch; specific cell ... See more keywords