The crosstalk between PTEN-induced kinase 1-mediated mitophagy and the inflammasome in the pathogenesis of alopecia areata.
Sign Up to like & getrecommendations! Published in 2023 at "Experimental dermatology"
DOI: 10.1111/exd.14844
Abstract: Alopecia areata (AA) is a T-cell-mediated autoimmune disease that causes chronic, relapsing hair loss; however, its precise pathogenesis remains to be elucidated. Recent studies have provided compelling evidence of crosstalk between inflammasomes and mitophagy-a process… read more here.
Keywords: pten induced; ors cells; inflammasome activation; crosstalk ... See more keywords
Defective PTEN-induced kinase 1/Parkin mediated mitophagy and neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.1031153
Abstract: The selective degradation of mitochondria through mitophagy is a crucial process for maintaining mitochondrial function and cellular health. Mitophagy is a specialized form of selective autophagy that uses unique machinery to recognize and target damaged… read more here.
Keywords: defective pten; kinase parkin; pten induced; induced kinase ... See more keywords