PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage.
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DOI: 10.1158/2159-8290.cd-18-0083
Abstract: The function of PTEN in the cytoplasm largely depends on its lipid-phosphatase activity by antagonizing the PI3K-Akt oncogenic pathway. However, molecular mechanism(s) underlying the role of PTEN in the nucleus remain largely elusive. Here, we… read more here.
Keywords: methylation; pten; dna damage; pten methylation ... See more keywords