Articles with "pten mut" as a keyword



Real-world patient (pt) characteristics, treatment patterns, and overall survival (OS) in metastatic hormone-sensitive prostate cancer (mHSPC): Insights by PTEN status.

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Published in 2025 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2025.43.16_suppl.5096

Abstract: 5096 Background: The loss of function of the tumor suppressor gene PTEN is associated with an increased risk of recurrence and poor clinical outcomes in advanced prostate cancer (PC). Current understanding of PTEN prevalence and… read more here.

Keywords: characteristics treatment; pten; pten homs; homs del ... See more keywords
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Identification of the Prognostic Signatures of Glioma With Different PTEN Status

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Published in 2021 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2021.633357

Abstract: The high-grade glioma is characterized by cell heterogeneity, gene mutations, and poor prognosis. The deletions and mutations of the tumor suppressor gene PTEN (5%-40%) in glioma patients are associated with worse survival and therapeutic resistance.… read more here.

Keywords: pten mut; glioma; different pten; pten status ... See more keywords