PTEN Down‐Regulation Promotes β‐Oxidation to Fuel Hypertrophic Liver Growth After Hepatectomy in Mice
Sign Up to like & getrecommendations! Published in 2017 at "Hepatology"
DOI: 10.1002/hep.29226
Abstract: In regenerating liver, hepatocytes accumulate lipids before the major wave of parenchymal growth. This transient, regeneration‐associated steatosis (TRAS) is required for liver recovery, but its purpose is unclear. The tumor suppressor phosphatase and tensin homolog… read more here.
Keywords: liver growth; oxidation; hypertrophic liver; liver ... See more keywords
Targeting PTEN Regulation by Post Translational Modifications
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14225613
Abstract: Simple Summary Cancer cells accumulate genetic alterations that improve their proliferation, survival, and migration capabilities. One of the most frequently altered signaling nodes in human cancer is the PI3-kinase /PTEN pathway. Most therapeutic efforts thus… read more here.
Keywords: translational modifications; pi3 kinase; post translational; kinase ... See more keywords