Impact of PTEN/SOCS3 deletion on amelioration of dendritic shrinkage of retinal ganglion cells after optic nerve injury.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental eye research"
DOI: 10.1016/j.exer.2020.107938
Abstract: Retinal ganglion cell (RGC) degeneration, leading to irreversible blindness in chronic optic neuropathies such as glaucoma, begins with dendritic shrinkage followed by axon degeneration. Although limited axon regeneration in the optic nerve is possible with… read more here.
Keywords: deletion; pten socs3; thy yfp; optic nerve ... See more keywords
Modest enhancement of sensory axon regeneration in the sciatic nerve with conditional co-deletion of PTEN and SOCS3 in the dorsal root ganglia of adult mice
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2018.02.012
Abstract: ABSTRACT Axons within the peripheral nervous system are capable of regeneration, but full functional recovery is rare. Recent work has shown that conditional deletion of two key signaling inhibitors of the PI3K and Jak/Stat pathways—phosphatase… read more here.
Keywords: pten socs3; crush; regeneration; deletion ... See more keywords