Diverse Macrophages Constituted the Glioma Microenvironment and Influenced by PTEN Status
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DOI: 10.3389/fimmu.2022.841404
Abstract: The glioma immune microenvironment (GIM), consisting of glioma cells, stromal cells, and immune cells, accelerates the initiation, development, immune evasion, chemoresistance, and radioresistance of glioblastoma (GBM), whereas the immunosuppressive mechanisms of GBM have not been… read more here.
Keywords: microenvironment; diverse macrophages; pten status; glioma ... See more keywords
Identification of the Prognostic Signatures of Glioma With Different PTEN Status
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DOI: 10.3389/fonc.2021.633357
Abstract: The high-grade glioma is characterized by cell heterogeneity, gene mutations, and poor prognosis. The deletions and mutations of the tumor suppressor gene PTEN (5%-40%) in glioma patients are associated with worse survival and therapeutic resistance.… read more here.
Keywords: pten mut; glioma; different pten; pten status ... See more keywords