Pterostilbene inhibits amyloid‐β‐induced neuroinflammation in a microglia cell line by inactivating the NLRP3/caspase‐1 inflammasome pathway
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27023
Abstract: Neuroinflammation has been known as an important pathogenetic contributor of Alzheimer's disease (AD). Pterostilbene is a natural compound which has neuroprotective activity. However, the effect of pterostilbene on amyloid‐β (Aβ)‐induced neuroinflammation has not been clarified.… read more here.
Keywords: nlrp3 caspase; caspase inflammasome; neuroinflammation; induced neuroinflammation ... See more keywords
Pterostilbene Inhibits Lipogenic Activity similar to Resveratrol or Caffeine but Differently Modulates Lipolysis in Adipocytes
Sign Up to like & getrecommendations! Published in 2017 at "Phytotherapy Research"
DOI: 10.1002/ptr.5852
Abstract: The anti‐obesity effects of resveratrol shown in rodents are not transposed into an efficient therapy of human obesity. Consequently, the search for molecules mimicking or surpassing resveratrol actions is ongoing. The natural phenolic compound pterostilbene… read more here.
Keywords: insulin; resveratrol; glucose uptake; pterostilbene ... See more keywords
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
Sign Up to like & getrecommendations! Published in 2021 at "Cell biology and toxicology"
DOI: 10.1007/s10565-021-09635-8
Abstract: Hepatocyte senescence is a key event participating in the progression of alcoholic liver disease. Autophagy is a critical biological process that controls cell fates by affecting cell behaviors like senescence. Pterostilbene is a natural compound… read more here.
Keywords: hepatocyte senescence; alcoholic liver; senescence; pterostilbene ... See more keywords
Profile of pterostilbene-induced redox homeostasis modulation in cardiac myoblasts and heart tissue
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biosciences"
DOI: 10.1007/s12038-018-9815-9
Abstract: This study was designed to investigate the effect of pterostilbene (PTS) on cardiac oxidative stress in vitro, as this is a simple and promising methodology to study cardiac disease. Cardiac myoblasts (H9c2 cells) and homogenised… read more here.
Keywords: cardiac tissue; pterostilbene; tissue; ros levels ... See more keywords
Effects of resveratrol and its analogue pterostilbene, on NOV/CCN3 adipokine in adipose tissue from rats fed a high-fat high-sucrose diet
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Physiology and Biochemistry"
DOI: 10.1007/s13105-019-00680-w
Abstract: Nephroblastoma overexpressed protein, also called NOV/CCN3, is an adipokine which is present in various tissues and recently linked to obesity. The objective of the study was to determine the effect of resveratrol and pterostilbene on… read more here.
Keywords: nov ccn3; pterostilbene; adipose tissue; rats fed ... See more keywords
In vitro and in vivo evaluation of pterostilbene for the management of diabetic complications
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Ayurveda and Integrative Medicine"
DOI: 10.1016/j.jaim.2018.01.003
Abstract: Background Aldose reductase (AR) and Advanced glycation end product (AGE) are known to play important roles in the development of diabetic complications. The inhibitors of AR and AGE would be potential agents for the prevention… read more here.
Keywords: pterostilbene management; evaluation pterostilbene; vitro vivo; pterostilbene ... See more keywords
Biological activity of pterostilbene against Peronophythora litchii, the litchi downy blight pathogen
Sign Up to like & getrecommendations! Published in 2018 at "Postharvest Biology and Technology"
DOI: 10.1016/j.postharvbio.2018.05.011
Abstract: Abstract Peronophythora litchii, the oomycete pathogen of litchi downy blight, infects leaves, flowers and fruits of litchi at pre-harvest stage, while the greatest economic loss was caused at postharvest stage, due to infection occurring during… read more here.
Keywords: downy blight; pterostilbene; litchii; litchi downy ... See more keywords
Triad3A-Dependent TLR4 Ubiquitination and Degradation Contributes to the Anti-Inflammatory Effects of Pterostilbene on Vascular Dementia.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c01219
Abstract: Pterostilbene, a methylated stilbene derived from many plant foods, has significant anti-inflammatory activity. Meanwhile, vascular dementia (VaD) is the second most common subtype of dementia, in which inflammation is one of the major pathogenic contributors.… read more here.
Keywords: anti inflammatory; vascular dementia; degradation; tlr4 ... See more keywords
Comprehensive Analysis of Pterostilbene Metabolites In Vivo and In Vitro Using a UHPLC-Q-Exactive Plus Mass Spectrometer with Multiple Data-Mining Methods
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c03924
Abstract: Pterostilbene, a stilbene phytoalexin, is mainly obtained from blueberries and grape vines; however, its metabolic mechanisms were unclear in vivo. In the present study, three different methods were used to prepare biological samples, and then,… read more here.
Keywords: analysis pterostilbene; pterostilbene metabolites; pterostilbene; vivo vitro ... See more keywords
Pterostilbene, a natural phenolic compound, synergizes the antineoplastic effects of megestrol acetate in endometrial cancer
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DOI: 10.1038/s41598-017-12922-2
Abstract: Endometrial cancer is the most common gynecologic cancer in the United States and its incidence and mortality has been rising over the past decade. Few treatment options are available for patients with advanced and recurring… read more here.
Keywords: acetate endometrial; pterostilbene; endometrial cancer; cancer ... See more keywords
Pterostilbene exert an anti-arthritic effect by attenuating inflammation, oxidative stress, and alteration of gut microbiota.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.14011
Abstract: Pterostilbene is a revesterol analog with a long bioavailability and having potent anti-inflammatory activity in animal studies. In this study, we tried to scrutinize the anti-arthritic effect of pterostilbene against complete Freund's adjuvant (CFA)-induced arthritis… read more here.
Keywords: arthritic effect; anti arthritic; pterostilbene; gut microbiota ... See more keywords