Pterostilbene Exhibited the Anticancer Effect Against 1, 2‐Dimethylhydrazine (DMH)‐Induced Colorectal Cancer via Alteration of Oxidative Stress, Inflammation and Gut Microbiota
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.70123
Abstract: Colorectal cancer (CRC) is the third leading cause of cancer‐related deaths worldwide. The current investigation aimed to assess the chemoprotective effects of pterostilbene against 1,2‐dimethylhydrazine (DMH)‐induced colorectal cancer in mice. An in‐silico study was conducted… read more here.
Keywords: colorectal cancer; cancer; pterostilbene; dimethylhydrazine dmh ... See more keywords
Pterostilbene inhibits amyloid‐β‐induced neuroinflammation in a microglia cell line by inactivating the NLRP3/caspase‐1 inflammasome pathway
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27023
Abstract: Neuroinflammation has been known as an important pathogenetic contributor of Alzheimer's disease (AD). Pterostilbene is a natural compound which has neuroprotective activity. However, the effect of pterostilbene on amyloid‐β (Aβ)‐induced neuroinflammation has not been clarified.… read more here.
Keywords: nlrp3 caspase; caspase inflammasome; neuroinflammation; induced neuroinflammation ... See more keywords
Pterostilbene Inhibits Lipogenic Activity similar to Resveratrol or Caffeine but Differently Modulates Lipolysis in Adipocytes
Sign Up to like & getrecommendations! Published in 2017 at "Phytotherapy Research"
DOI: 10.1002/ptr.5852
Abstract: The anti‐obesity effects of resveratrol shown in rodents are not transposed into an efficient therapy of human obesity. Consequently, the search for molecules mimicking or surpassing resveratrol actions is ongoing. The natural phenolic compound pterostilbene… read more here.
Keywords: insulin; resveratrol; glucose uptake; pterostilbene ... See more keywords
Discovery of novel pterostilbene/biphenyl tethered 5-FU based conjugates targeting colorectal cancer: synthesis, cytotoxic and ADMET modeling studies
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DOI: 10.1007/s00044-025-03401-9
Abstract: A new series of conjugates linking 5-FU with parts of pterostilbene and biphenyl were designed, and synthesized, besides, their biological activity was assessed against human colorectal adenocarcinoma cells (SW480) and the non-malignant cell line NCM460.… read more here.
Keywords: colorectal cancer; cancer; pterostilbene; pterostilbene biphenyl ... See more keywords
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
Sign Up to like & getrecommendations! Published in 2021 at "Cell biology and toxicology"
DOI: 10.1007/s10565-021-09635-8
Abstract: Hepatocyte senescence is a key event participating in the progression of alcoholic liver disease. Autophagy is a critical biological process that controls cell fates by affecting cell behaviors like senescence. Pterostilbene is a natural compound… read more here.
Keywords: hepatocyte senescence; alcoholic liver; senescence; pterostilbene ... See more keywords
Profile of pterostilbene-induced redox homeostasis modulation in cardiac myoblasts and heart tissue
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biosciences"
DOI: 10.1007/s12038-018-9815-9
Abstract: This study was designed to investigate the effect of pterostilbene (PTS) on cardiac oxidative stress in vitro, as this is a simple and promising methodology to study cardiac disease. Cardiac myoblasts (H9c2 cells) and homogenised… read more here.
Keywords: cardiac tissue; pterostilbene; tissue; ros levels ... See more keywords
Effects of resveratrol and its analogue pterostilbene, on NOV/CCN3 adipokine in adipose tissue from rats fed a high-fat high-sucrose diet
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Physiology and Biochemistry"
DOI: 10.1007/s13105-019-00680-w
Abstract: Nephroblastoma overexpressed protein, also called NOV/CCN3, is an adipokine which is present in various tissues and recently linked to obesity. The objective of the study was to determine the effect of resveratrol and pterostilbene on… read more here.
Keywords: nov ccn3; pterostilbene; adipose tissue; rats fed ... See more keywords
In vitro and in vivo evaluation of pterostilbene for the management of diabetic complications
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Ayurveda and Integrative Medicine"
DOI: 10.1016/j.jaim.2018.01.003
Abstract: Background Aldose reductase (AR) and Advanced glycation end product (AGE) are known to play important roles in the development of diabetic complications. The inhibitors of AR and AGE would be potential agents for the prevention… read more here.
Keywords: pterostilbene management; evaluation pterostilbene; vitro vivo; pterostilbene ... See more keywords
Biological activity of pterostilbene against Peronophythora litchii, the litchi downy blight pathogen
Sign Up to like & getrecommendations! Published in 2018 at "Postharvest Biology and Technology"
DOI: 10.1016/j.postharvbio.2018.05.011
Abstract: Abstract Peronophythora litchii, the oomycete pathogen of litchi downy blight, infects leaves, flowers and fruits of litchi at pre-harvest stage, while the greatest economic loss was caused at postharvest stage, due to infection occurring during… read more here.
Keywords: downy blight; pterostilbene; litchii; litchi downy ... See more keywords
Triad3A-Dependent TLR4 Ubiquitination and Degradation Contributes to the Anti-Inflammatory Effects of Pterostilbene on Vascular Dementia.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c01219
Abstract: Pterostilbene, a methylated stilbene derived from many plant foods, has significant anti-inflammatory activity. Meanwhile, vascular dementia (VaD) is the second most common subtype of dementia, in which inflammation is one of the major pathogenic contributors.… read more here.
Keywords: anti inflammatory; vascular dementia; degradation; tlr4 ... See more keywords
Pterostilbene Potentiates the NGF-TrkA Signaling Pathway, Enhancing Differentiation in PC12 Cells.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.4c10766
Abstract: Pterostilbene, a stilbenoid found in vegetables and natural products, has therapeutic potential due to its multiple pharmacological actions. In the brain, the nerve growth factor (NGF) is a pivotal neurotrophic factor, serving for neuronal survival… read more here.
Keywords: differentiation; pc12 cells; pterostilbene; ngf trka ... See more keywords