Effects of parathyroidectomy on plasma PTH fragments and heart rate variability in stage 5 chronic kidney disease patients
Sign Up to like & getrecommendations! Published in 2021 at "Renal Failure"
DOI: 10.1080/0886022x.2021.1931318
Abstract: Abstract Introduction Circulating intact parathyroid hormone (iPTH) levels include full-length (1-84) PTH and long C-PTH fragments, but primarily (7-84) PTH, which have been reported to have antagonistic effects on the bones and kidneys. However, their… read more here.
Keywords: pth levels; heart rate; pth; plasma pth ... See more keywords
Chemical Characterization and Quantification of Circulating Intact PTH and PTH Fragments by High-Resolution Mass Spectrometry in Chronic Renal Failure
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Chemistry"
DOI: 10.1093/clinchem/hvab013
Abstract: Abstract Background The precise concentrations of full-length parathyroid hormone (PTH1-84) and the identity and concentrations of PTH fragments in patients with various stages of chronic renal failure are unknown. Methods We developed a liquid chromatography-high… read more here.
Keywords: pth; renal failure; chronic renal; pth fragments ... See more keywords
MON-536 Improving the Accuracy and Reliability of Parathyroid Hormone Measurements by Establishing a Mass Spectrometric Reference Measurement Procedure
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Endocrine Society"
DOI: 10.1210/js.2019-mon-536
Abstract: Abstract With a rising incidence in renal failure, chronic kidney disease (CKD) has become one of the leading health conditions in the U.S. The earlier stages of CKD generate few symptoms and only until the… read more here.
Keywords: intact pth; pth; mass; parathyroid hormone ... See more keywords
High-Resolution Mass Spectrometry for the Measurement of PTH and PTH Fragments: Insights into PTH Physiology and Bioactivity.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Society of Nephrology : JASN"
DOI: 10.1681/asn.2022010036
Abstract: Full-length parathyroid hormone (PTH 1-84) is crucial for the regulation of calcium and phosphate homeostasis and bone remodeling. PTH 1-84 is metabolized into various PTH fragments, which are measured with varying levels of efficiency by… read more here.
Keywords: pth fragments; mass spectrometry; physiology; bioactivity ... See more keywords