LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "ptk6" as a keyword



Bioinformatics-based prognostic value and in vitro functional validation of PTK6 in cutaneous melanoma

Sign Up to like & get
recommendations! Published in 2025 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2025.1555302

Abstract: Background Cutaneous melanoma (CM) is a highly malignant tumor originating from melanocytes. Rising incidence rates pose a significant burden on global health and economy. Advanced CM patients face poor prognosis due to high recurrence and… read more here.

Keywords: role; analysis; risk; ptk6 ... See more keywords

Breast Tumour Kinase (Brk/PTK6) Contributes to Breast Tumour Xenograft Growth and Modulates Chemotherapeutic Responses In Vitro

Sign Up to like & get
recommendations! Published in 2022 at "Genes"

DOI: 10.3390/genes13030402

Abstract: Breast tumour kinase (Brk/PTK6) is overexpressed in up to 86% of breast cancers and is associated with poorer patient outcomes. It is considered a potential therapeutic target in breast cancer, even though the full spectrum… read more here.

Keywords: growth; breast tumour; ptk6; kinase ... See more keywords

Epigenetic Deregulation of Protein Tyrosine Kinase 6 Promotes Carcinogenesis of Oral Squamous Cell Carcinoma

Sign Up to like & get
recommendations! Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23094495

Abstract: Oral squamous cell carcinoma (OSCC) accounts for over 90% of oral cancers and causes considerable morbidity and mortality. Epigenetic deregulation is a common mechanism underlying carcinogenesis. DNA methylation deregulation is the epigenetic change observed during… read more here.

Keywords: cell; methylation; ptk6; deregulation ... See more keywords

The associated pyrazolopyrimidines PP1 and PP2 inhibit protein tyrosine kinase 6 activity and suppress breast cancer cell proliferation.

Sign Up to like & get
recommendations! Published in 2017 at "Oncology letters"

DOI: 10.3892/ol.2017.5564

Abstract: Protein tyrosine kinase (PTK)6, also known as breast tumor kinase, is a non-receptor tyrosine kinase. It is closely associated with, but evolutionarily distinct from, the Src family members. PTK6 has a role in proliferation, migration… read more here.

Keywords: breast; kinase; ptk6; protein tyrosine ... See more keywords