Articles with "ptk7 mabs" as a keyword



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Anti-PTK7 Monoclonal Antibodies Exhibit Anti-Tumor Activity at the Cellular Level and in Mouse Xenograft Models of Esophageal Squamous Cell Carcinoma

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms232012195

Abstract: PTK7 is a catalytically defective receptor protein tyrosine kinase upregulated in various cancers, including esophageal squamous cell carcinoma (ESCC). In previous studies, we observed a positive correlation between PTK7 expression levels and tumorigenicity in various… read more here.

Keywords: mouse xenograft; cell; ptk7 mabs; esophageal squamous ... See more keywords