Articles with "ptk7 trop2" as a keyword



Abstract LB216: Discovery of BCG033, a novel anti-PTK7 x TROP2 bispecific antibody-drug conjugate with promising efficacy against triple-negative breast cancer

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-lb216

Abstract: Triple-negative breast cancer (TNBC) accounts for 15-20% of metastatic breast cancer incidence, and remains an area of unmet clinical need due to the low rates of overall survival. Recently, the TROP2-targeting ADC sacituzumab govitecan has… read more here.

Keywords: ptk7 trop2; breast cancer; tnbc; ptk7 ... See more keywords