Mapping of barley susceptibility/resistance QTL against spot form net blotch caused by Pyrenophora teres f. maculata using RIL populations
Sign Up to like & getrecommendations! Published in 2019 at "Theoretical and Applied Genetics"
DOI: 10.1007/s00122-019-03328-x
Abstract: Spot form net blotch (SFNB) caused by the necrotrophic fungal pathogen Pyrenophora teres f. maculata (Ptm) is an important disease of barley worldwide including the major barley production regions of North America. To characterize SFNB… read more here.
Keywords: ril populations; susceptibility; barley; resistance ... See more keywords
Nanotechnological approaches for pentamidine delivery
Sign Up to like & getrecommendations! Published in 2022 at "Drug Delivery and Translational Research"
DOI: 10.1007/s13346-022-01127-4
Abstract: Pentamidine (PTM), which is a diamine that is widely known for its antimicrobial activity, is a very interesting drug whose mechanism of action is not fully understood. In recent years, PTM has been proposed as… read more here.
Keywords: approaches pentamidine; drug; delivery; ptm ... See more keywords
Olfactory responses of adult Potato Tuber Moth, Phthorimaea operculella (Zeller) measured by attraction relative to the tomato leaf volatiles
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Asia-Pacific Entomology"
DOI: 10.1016/j.aspen.2019.04.007
Abstract: Abstract The potato tuber moth (PTM) is an oligophagous herbivore and a severe pest of solanaceous crops in many countries of the world. Previously, we reported host expansion and damage potential of PTM on tomato,… read more here.
Keywords: tomato leaf; potato tuber; ptm; tomato ... See more keywords
Enrichment of oxidised peptides of oxidised allows identification of oxidized cysteine residues in signaling proteins in vivo
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.10.118
Abstract: Detection of oxidative post-translational modifications (ox-PTMs) of Cys residues in mammalian signaling proteins in vivo is one of the current challenges in redox biology. Ox-PTM residues labeling using maleimide switch methods coupled to mass spectrometry… read more here.
Keywords: cys; proteins vivo; biology; signaling proteins ... See more keywords
Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c01076
Abstract: Post-translational modification (PTM) on protein plays important roles in the regulation of cellular function and disease pathogenesis. The systematic analysis of PTM dynamics presents great opportunities to enlarge the target space by PTM allosteric regulation.… read more here.
Keywords: post translational; translational modification; drug design; kinase family ... See more keywords
FAIMS Enhances the Detection of PTM Crosstalk Sites
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Proteome Research"
DOI: 10.1021/acs.jproteome.1c00721
Abstract: Protein post-translational modifications (PTMs) enable cells to rapidly change in response to biological stimuli. With hundreds of different PTMs, understanding these control mechanisms is complex. To date, efforts have focused on investigating the effect of… read more here.
Keywords: crosstalk sites; detection ptm; ptm crosstalk; crosstalk ... See more keywords
Cryptic and Stereospecific Hydroxylation, Oxidation, and Reduction in Platensimycin and Platencin Biosynthesis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.8b13452
Abstract: Platensimycin (PTM) and platencin (PTN) are highly functionalized bacterial diterpenoids of ent-kauranol and ent-atiserene biosynthetic origin. C7 oxidation in the B-ring plays a key biosynthetic role in generating structural complexity known for ent-kaurane and ent-atisane… read more here.
Keywords: platencin; biosynthesis; oxidation; hydroxyl ... See more keywords
A comparative metabologenomic approach reveals mechanistic insights into Streptomyces antibiotic crypticity
Sign Up to like & getrecommendations! Published in 2021 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2103515118
Abstract: Significance Streptomyces genomes harbor a trove of biosynthetic gene clusters (BGCs) that encode for drug-like molecules. However, only a fraction of these readily yield expected products. To investigate why this is, we used polycyclic tetramate… read more here.
Keywords: production; ptm producers; antibiotic crypticity; approach ... See more keywords
PTMint database of experimentally verified PTM regulation on protein–protein interaction
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac823
Abstract: Abstract Motivation Post-translational modification (PTM) is an important biochemical process. which includes six most well-studied types: phosphorylation, acetylation, methylation, sumoylation, ubiquitylation and glycosylation. PTM is involved in various cell signaling pathways and biological processes. Abnormal… read more here.
Keywords: protein protein; database; ptmint; regulation ... See more keywords
MusiteDeep: a deep-learning based webserver for protein post-translational modification site prediction and visualization
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa275
Abstract: Abstract MusiteDeep is an online resource providing a deep-learning framework for protein post-translational modification (PTM) site prediction and visualization. The predictor only uses protein sequences as input and no complex features are needed, which results… read more here.
Keywords: ptm; deep learning; site; prediction ... See more keywords
qPTM: an updated database for PTM dynamics in human, mouse, rat and yeast
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac820
Abstract: Abstract Post-translational modifications (PTMs) are critical molecular mechanisms that regulate protein functions temporally and spatially in various organisms. Since most PTMs are dynamically regulated, quantifying PTM events under different states is crucial for understanding biological… read more here.
Keywords: qptm; updated database; qptm updated; database ptm ... See more keywords